NCT01682551 is a Phase 2 clinical trial of Chinese Medicine in Acute Mountain Sickness (AMS), sponsored by China Medical University Hospital.

Who is sponsoring NCT01682551?

NCT01682551 is sponsored by China Medical University Hospital.

What drugs are being tested in NCT01682551?

Interventions in NCT01682551: Chinese Medicine, Acetalozamide.

What condition does NCT01682551 study?

NCT01682551 studies Acute Mountain Sickness (AMS).

Is NCT01682551 still recruiting?

NCT01682551 is currently status unknown. Last updated 13 September 2012.

Last reviewed 2012-09-13 · How we verify

NCT01682551

Name: Drug Landscape Pharmaceutical Database
Creator: Drug Landscape
Published: 2026-01-01
License: https://creativecommons.org/licenses/by/4.0/

Evaluation of the Prevention and Treatment Effects of Chinese Medicine on High Altitude Illness

Status unknown Phase 2 Last updated 13 September 2012

What this trial tests

Phase 2 trial testing Chinese Medicine in Acute Mountain Sickness (AMS) in 240 participants. Status unknown.

Timeline

1 September 2012

Primary endpoint
1 September 2012

1 September 2012

Quick facts

Lead sponsor	China Medical University Hospital
Phase	Phase 2
Status	Status unknown
Study type	INTERVENTIONAL
Allocation	randomized
Design	parallel
Masking	quadruple
Primary purpose	prevention
Enrollment	240
Start date	1 September 2012
Primary completion	1 September 2012
Estimated completion	1 September 2012
Sites	1 location across Taiwan

Drugs / interventions tested

Chinese Medicine
Acetalozamide — full drug profile →

Conditions studied

Acute Mountain Sickness (AMS) — all drugs for Acute Mountain Sickness (AMS) →

Sponsor

China Medical University Hospital

Who can join

Adults 20 to 70, any sex, with Acute Mountain Sickness (AMS). Healthy volunteers can join.

What's being measured

Primary outcomes are the specific endpoints the trial is designed to prove or disprove.

The incidence of AMS will be measured by the Lake Louise Self Report (Lake Louise Score ≥4 with headache)
Time frame: The Lake Louise Score will be measured in the noon of the second day after hiking to determine the onset of AMS.
The investigators will take the participators in Hehuan mountain for two days hike (24 hours) and an overnight over 3,000m. The Lake Louise score will measure before and after hiking.

Sponsor's own description

This trial is aimed to evaluate the effects of "Wu Zhu Yu Tang" on the prevention of Acute Mountain Sickness(AMS).

Publications & conference data

3 peer-reviewed publications reference this trial (live from Europe PMC):

Interventions for preventing high altitude illness: Part 1. Commonly-used classes of drugs.
Nieto Estrada VH, Molano Franco D, Medina RD, Gonzalez Garay AG, et al · · 2017 · cited 37× · PMID 28653390 · DOI 10.1002/14651858.cd009761.pub2
Interventions for preventing high altitude illness: Part 3. Miscellaneous and non-pharmacological interventions.
Molano Franco D, Nieto Estrada VH, Gonzalez Garay AG, Martí-Carvajal AJ, et al · · 2019 · cited 15× · PMID 31012483 · DOI 10.1002/14651858.cd013315
Interventions for preventing high altitude illness: Part 2. Less commonly-used drugs.
Gonzalez Garay A, Molano Franco D, Nieto Estrada VH, Martí-Carvajal AJ, et al · · 2018 · cited 8× · PMID 29529715 · DOI 10.1002/14651858.cd012983

Verify or expand the search:

Other trials of Chinese Medicine

Trials testing the same drug.

NCT04448197 — Insomnia Treated by Traditional Chinese Medicine and Its Circadian Rhythm · completed

Other recruiting trials for Acute Mountain Sickness (AMS)

Currently open trials in the same condition.

NCT07517068 — The Role of Acetazolamide in Mitigating Inflammation and Innate Immune Activation at High Altitude · EARLY_PHASE1 · active not recruiting
NCT07118462 — HighCycle Study: Acetazolamide, High Altitude and Plasma Volume · Phase 4 · recruiting

Other China Medical University Hospital trials

Trials by the same sponsor.

NCT07525700 — The Effects of Combining Electronic Picture Books With RPG-Based Gamified Learning on Nursing Students' Motivation and L · NA · not yet recruiting
NCT07463391 — Chinese Classics Recitation Training in Subjective Cognitive Decline · NA · not yet recruiting
NCT07482189 — Effectiveness and Efficiency of an Upper Limb Active-Passive Exoskeleton Robot in Patients With Frozen Shoulder · NA · not yet recruiting
NCT07437144 — Exploring the Effects of Shangshou Daoyin Method on Improving Sleep Quality, Quality of Life, and TCM Constitution in Br · NA · not yet recruiting
NCT07232667 — Digital Technology for Active and Healthy Ageing in Taiwan · NA · not yet recruiting

Verify against primary sources

ClinicalTrials.gov — authoritative US registry record
WHO ICTRP — international registry index
EU Clinical Trials Register
Sponsor press releases (Google)

Data sources for this page

Trial protocol + status: ClinicalTrials.gov NCT01682551 (US National Library of Medicine, public domain)
Publications: Europe PMC API search by NCT ID, retrieved 10 June 2026
Drug + disease cross-links: matched in real time against Drug Landscape's normalised drug + company + condition tables
Sponsor: as reported to ClinicalTrials.gov by China Medical University Hospital
Last refreshed: 13 September 2012

Drug Landscape aggregates and links these public records for informational use only. Always verify against the primary source before clinical or regulatory decisions. Canonical URL: https://druglandscape.com/trial/NCT01682551.

Primary sources · FDA · ClinicalTrials.gov · EMA · SEC EDGAR · ChEMBL · Wikidata · full sourcing