NCT01552798 (Tarot Headache) is a Phase 3 clinical trial of Acetylsalicylic acid (Aspirin, BAY1019036) in Headache, sponsored by Bayer.

Who is sponsoring NCT01552798?

NCT01552798 is sponsored by Bayer.

What drugs are being tested in NCT01552798?

Interventions in NCT01552798: Acetylsalicylic acid (Aspirin, BAY1019036), Acetaminophen, Placebo.

Is NCT01552798 still recruiting?

NCT01552798 is currently terminated. Last updated 19 December 2018.

Last reviewed 2018-12-19 · How we verify

NCT01552798: Tarot Headache

Name: Drug Landscape Pharmaceutical Database
Creator: Drug Landscape
Published: 2026-01-01
License: https://creativecommons.org/licenses/by/4.0/

Efficacy of a Single Dose of Aspirin vs. Acetaminophen in Tension Type Headache

Terminated Phase 3 Last updated 19 December 2018

What this trial tests

Phase 3 trial testing Acetylsalicylic acid (Aspirin, BAY1019036) in Headache in 9 participants. Terminated before completion.

Timeline

12 March 2012

Primary endpoint
4 June 2012

4 June 2012

Quick facts

Lead sponsor	Bayer
Phase	Phase 3
Status	Terminated
Study type	INTERVENTIONAL
Allocation	randomized
Design	parallel
Masking	triple
Primary purpose	treatment
Enrollment	9
Start date	12 March 2012
Primary completion	4 June 2012
Estimated completion	4 June 2012
Sites	1 location across United States

Drugs / interventions tested

Acetylsalicylic acid (Aspirin, BAY1019036) — full drug profile →
Acetaminophen (Paracetamol) — full drug profile →
Placebo

Conditions studied

Headache — all drugs for Headache →

Sponsor

Bayer — full company profile →

Who can join

Adults 18 to 65, any sex, with Headache. Patients with the condition only — healthy volunteers not accepted.

Sponsor's own description

The purpose of this trial is to determine if a single, oral dose of a fast release aspirin 1000 mg provides relief compared to acetaminophen 1000 mg and placebo in subjects with tension-type headache pain.

Publications & conference data

2 peer-reviewed publications reference this trial (live from Europe PMC):

Paracetamol (acetaminophen) for acute treatment of episodic tension-type headache in adults.
Stephens G, Derry S, Moore RA. · · 2016 · cited 27× · PMID 27306653 · DOI 10.1002/14651858.cd011889.pub2
Aspirin for acute treatment of episodic tension-type headache in adults.
Derry S, Wiffen PJ, Moore RA. · · 2017 · cited 15× · PMID 28084009 · DOI 10.1002/14651858.cd011888.pub2

Verify or expand the search:

Other trials of Acetylsalicylic acid (Aspirin, BAY1019036)

Trials testing the same drug.

NCT02313909 — Rivaroxaban Versus Aspirin in Secondary Prevention of Stroke and Prevention of Systemic Embolism in Patients With Recent · Phase 3 · terminated

Other recruiting trials for Headache

Currently open trials in the same condition.

NCT07487649 — Treatment Response in Patients With Medication-Overuse Headache · recruiting
NCT07097792 — Concussion Recovery and Support Program · NA · recruiting
NCT06225817 — Placebo Impacts Sleep and Pain Modulation in Chronic Pain · NA · recruiting
NCT06310200 — Sphenopalatine Ganglion Block and Cold Induced Headaches · Phase 1 · active not recruiting
NCT07404956 — THE EFFECT OF SURGICAL MASK AND N95 MASK USE ON SURGICAL SMOKE IN OPERATING ROOM NURSES · NA · recruiting

Other Bayer trials

Trials by the same sponsor.

NCT05900388 — A Study to Observe the Pattern of Use and Safety of Rivaroxaban in Children Under 2 Years Old With Venous Thromboembolis · not yet recruiting
NCT07490431 — An Observational Study to Learn More About How Elinzanetant is Used and How Well it Works for Women With Menopause Sympt · not yet recruiting
NCT05477953 — An Observational Pregnancy Safety Study in Women Who Were Exposed to the Drug Nifurtimox During Pregnancy to Learn About · not yet recruiting
NCT07192952 — A Study to Learn More About How Safe Finerenone is, When it is Taken for a Longer Time With Standard Treatment, in Child · Phase 3 · not yet recruiting
NCT07450599 — A Study to Learn How Well a Combination of Darolutamide and Androgen Deprivation Therapy (ADT) Works as a Treatment Befo · Phase 2 · not yet recruiting

Verify against primary sources

ClinicalTrials.gov — authoritative US registry record
WHO ICTRP — international registry index
EU Clinical Trials Register
Sponsor press releases (Google)

Data sources for this page

Trial protocol + status: ClinicalTrials.gov NCT01552798 (US National Library of Medicine, public domain)
Publications: Europe PMC API search by NCT ID, retrieved 10 June 2026
Drug + disease cross-links: matched in real time against Drug Landscape's normalised drug + company + condition tables
Sponsor: as reported to ClinicalTrials.gov by Bayer
Last refreshed: 19 December 2018

Drug Landscape aggregates and links these public records for informational use only. Always verify against the primary source before clinical or regulatory decisions. Canonical URL: https://druglandscape.com/trial/NCT01552798.

Primary sources · FDA · ClinicalTrials.gov · EMA · SEC EDGAR · ChEMBL · Wikidata · full sourcing