NCT01546155 is a NA clinical trial of PET imaging in Healthy Controls, sponsored by Massachusetts General Hospital.

Who is sponsoring NCT01546155?

NCT01546155 is sponsored by Massachusetts General Hospital.

What drugs are being tested in NCT01546155?

Interventions in NCT01546155: PET imaging.

What condition does NCT01546155 study?

NCT01546155 studies Healthy Controls.

Is NCT01546155 still recruiting?

NCT01546155 is currently completed. Last updated 27 February 2017.

Are results published for NCT01546155?

Yes — primary outcome results have been posted to ClinicalTrials.gov. See the outcomes section above for details.

Last reviewed 2017-02-27 · How we verify

NCT01546155

Name: Drug Landscape Pharmaceutical Database
Creator: Drug Landscape
Published: 2026-01-01
License: https://creativecommons.org/licenses/by/4.0/

The Influence of Pressure Pain on [11C]Diprenorphine Binding Potentials

Completed NA Results posted Last updated 27 February 2017

What this trial tests

NA trial testing PET imaging in Healthy Controls in 11 participants. Completed in 1 December 2015.

Timeline

1 December 2011

Primary endpoint
1 October 2012

1 December 2015

Quick facts

Lead sponsor	Massachusetts General Hospital
Phase	NA
Status	Completed
Study type	INTERVENTIONAL
Allocation	na
Design	single group
Masking	none
Primary purpose	other
Enrollment	11
Start date	1 December 2011
Primary completion	1 October 2012
Estimated completion	1 December 2015
Sites	1 location across United States

Drugs / interventions tested

PET imaging

Conditions studied

Healthy Controls — all drugs for Healthy Controls →

Sponsor

Massachusetts General Hospital

Who can join

Adults 21 to 50, any sex, with Healthy Controls. Healthy volunteers can join.

What's being measured

Primary outcomes are the specific endpoints the trial is designed to prove or disprove.

PET/MRI Brain Activation
Time frame: day one
Simultaneously collect fMRI-PET data in humans to investigate the change between bold signal evoked by pressure pain and bold signal evoked by non-painful pressure. The PET analyses generates one value per 120 minutes. This value is compared to the other 120 minute scan PET value in order to reflect the change.

Sponsor's own description

Healthy volunteers aged 21 to 50 are needed for a research study investigating whether pain will alter the binding properties of (\[11C\]diprenorphine), a molecule that can be used during brain imaging. Positron Emission Tomography (PET) and functional Magnetic Resonance (fMRI) imaging will be used in this study.

Publications & conference data

No peer-reviewed publications indexed yet for this trial. Completed trials usually publish results within 12-18 months.

Verify or expand the search:

Other trials of PET imaging

Trials testing the same drug.

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NCT03434548 — IMarkHD: in Vivo Longitudinal Imaging of HD Pathology · recruiting
NCT04073810 — Residual Inflammation and Plaque Progression Long-term Evaluation · active not recruiting

Other recruiting trials for Healthy Controls

Currently open trials in the same condition.

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NCT06607432 — Temporal Interference Stimulation for Social Cognition · NA · recruiting

Other Massachusetts General Hospital trials

Trials by the same sponsor.

NCT03585946 — Outcomes in Stevens Johnsons Syndrome and Toxic Epidermal Necrolysis · withdrawn
NCT07214831 — A Feasibility and Acceptability Study of a Large Language Model-based Chatbot for Brief Alcohol Intervention Among Emerg · NA · not yet recruiting
NCT06686901 — A Randomized Controlled Trial of a Smartphone Delivered Treatment for Suicidal Thoughts and Behavior · NA · not yet recruiting
NCT05854212 — Behavioral Economics to Implement Nutrition Ranking in Food Pantries · NA · not yet recruiting
NCT07323446 — The MIND Study: The MGH/MIT Investigation of NAC on Dysregulation · EARLY_PHASE1 · not yet recruiting

Verify against primary sources

ClinicalTrials.gov — authoritative US registry record
WHO ICTRP — international registry index
EU Clinical Trials Register
Sponsor press releases (Google)

Data sources for this page

Trial protocol + status: ClinicalTrials.gov NCT01546155 (US National Library of Medicine, public domain)
Drug + disease cross-links: matched in real time against Drug Landscape's normalised drug + company + condition tables
Sponsor: as reported to ClinicalTrials.gov by Massachusetts General Hospital
Last refreshed: 27 February 2017

Drug Landscape aggregates and links these public records for informational use only. Always verify against the primary source before clinical or regulatory decisions. Canonical URL: https://druglandscape.com/trial/NCT01546155.

Primary sources · FDA · ClinicalTrials.gov · EMA · SEC EDGAR · ChEMBL · Wikidata · full sourcing