Last reviewed · How we verify

NCT01373866: MULTIMODHAL

Multimodal MRI-guided rTMS to Treat Refractory Hallucinations

Completed NA Last updated 26 December 2025
What this trial tests

NA trial testing MagPro X100 repetitive Transcranial Magnetic Stimulation in Hallucinations in 85 participants. Completed in 11 February 2022.

Timeline
15 November 2010
Primary endpoint
11 February 2022
11 February 2022

Quick facts

Lead sponsorUniversity Hospital, Lille
PhaseNA
StatusCompleted
Study typeINTERVENTIONAL
Allocationrandomized
Designparallel
Maskingtriple
Primary purposetreatment
Enrollment85
Start date15 November 2010
Primary completion11 February 2022
Estimated completion11 February 2022
Sites2 locations across France

Drugs / interventions tested

Conditions studied

Sponsor

University Hospital, Lille

Who can join

Adults 13 to 60, any sex, with Hallucinations or Schizophrenia. Patients with the condition only — healthy volunteers not accepted.

Sponsor's own description

* The efficacy of neuro-navigated rTMS for patients with schizophrenia suffering from drug-resistant multisensory hallucinations will be tested by the implementation of a double-blind randomized controlled trial (RCT) * This study will use a combination of different MRI modalities (fMRI and DTI) to define with precision rTMS brain-targets in the case of multisensory hallucinations * The investigators anticipate that multimodal MRI-guided rTMS will allow a significant improvement in the efficacy of neuromodulation treatment of refractory hallucinations

Publications & conference data

2 peer-reviewed publications reference this trial (live from Europe PMC):

  1. fMRI capture of auditory hallucinations: Validation of the two-steps method.
    Leroy A, Foucher JR, Pins D, Delmaire C, et al · · 2017 · cited 14× · PMID 28660668 · DOI 10.1002/hbm.23707
  2. Non-invasive Brain Stimulation and Auditory Verbal Hallucinations: New Techniques and Future Directions.
    Moseley P, Alderson-Day B, Ellison A, Jardri R, et al · · 2015 · cited 11× · PMID 26834541 · DOI 10.3389/fnins.2015.00515

Verify or expand the search:

Other University Hospital, Lille trials

Trials by the same sponsor.

Verify against primary sources

Data sources for this page

Drug Landscape aggregates and links these public records for informational use only. Always verify against the primary source before clinical or regulatory decisions. Canonical URL: https://druglandscape.com/trial/NCT01373866.

Primary sources · FDA · ClinicalTrials.gov · EMA · SEC EDGAR · ChEMBL · Wikidata · full sourcing