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NCT01255501
A First in Man Randomized Placebo Controlled Study of Single Ascending Intravenous Doses of NI-0701 in Healthy Volunteers
Phase 1 trial testing NI-0701 in Healthy Volunteers. Completed.
Quick facts
| Lead sponsor | Light Chain Bioscience - Novimmune SA |
|---|---|
| Phase | Phase 1 |
| Status | Completed |
| Study type | INTERVENTIONAL |
| Sites | 1 location across United Kingdom |
Drugs / interventions tested
- NI-0701 — full drug profile →
- Placebo
Conditions studied
- Healthy Volunteers — all drugs for Healthy Volunteers →
Sponsor
Light Chain Bioscience - Novimmune SA — full company profile →
Who can join
Adults 18 to 65, male only, with Healthy Volunteers. Healthy volunteers can join.
What's being measured
Primary outcomes are the specific endpoints the trial is designed to prove or disprove.
- Safety and tolerability of escalating single IV doses of NI-0701 in healthy volunteers
Sponsor's own description
The purpose of this study is to determine the safety, pharmacodynamic and pharmacokinetic profiles of a novel therapeutic drug when administered to healthy volunteers.
Publications & conference data
1 peer-reviewed publication reference this trial (live from Europe PMC):
-
Targeting CCL5 in inflammation.
Marques RE, Guabiraba R, Russo RC, Teixeira MM. · · 2013 · cited 285× · PMID 24090198 · DOI 10.1517/14728222.2013.837886
Verify or expand the search:
- PubMed search for NCT01255501
- Europe PMC full search
- ASCO Meeting Library
- ESMO Meeting Library
- bioRxiv preprints
- medRxiv preprints
- Google Scholar
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Other Light Chain Bioscience - Novimmune SA trials
Trials by the same sponsor.
- NCT05403554 — A Study of NI-1801 in Patients with Mesothelin Expressing Solid Cancers · Phase 1 · recruiting
- NCT03241108 — Study of an Anti-TLR4 mAb in Rheumatoid Arthritis · Phase 2 · completed
Verify against primary sources
- ClinicalTrials.gov — authoritative US registry record
- WHO ICTRP — international registry index
- EU Clinical Trials Register
- Sponsor press releases (Google)
- Trial protocol + status: ClinicalTrials.gov NCT01255501 (US National Library of Medicine, public domain)
- Publications: Europe PMC API search by NCT ID, retrieved 10 June 2026
- Drug + disease cross-links: matched in real time against Drug Landscape's normalised drug + company + condition tables
- Sponsor: as reported to ClinicalTrials.gov by Light Chain Bioscience - Novimmune SA
- Last refreshed: 6 December 2010
Drug Landscape aggregates and links these public records for informational use only. Always verify against the primary source before clinical or regulatory decisions. Canonical URL: https://druglandscape.com/trial/NCT01255501.
Primary sources · FDA · ClinicalTrials.gov · EMA · SEC EDGAR · ChEMBL · Wikidata · full sourcing