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NCT01178697
Three Injections of Intravitreal Bevasizumab Versus Two Injections of Intravitreal Triamcinolone in the Management of Branch Retinal Vein Occlusion
Phase 2 trial testing Bevasizumab in Central Retinal Vein Occlusion. Status unknown.
1 September 2010
Quick facts
| Lead sponsor | Shahid Beheshti University of Medical Sciences |
|---|---|
| Phase | Phase 2 |
| Status | Status unknown |
| Study type | INTERVENTIONAL |
| Allocation | randomized |
| Masking | single |
| Primary purpose | treatment |
| Start date | 1 January 2010 |
| Primary completion | 1 September 2010 |
| Estimated completion | 1 December 2010 |
| Sites | 1 location across Iran |
Drugs / interventions tested
- Bevasizumab — full drug profile →
- Triamcinolone Acetonide — full drug profile →
Conditions studied
- Central Retinal Vein Occlusion — all drugs for Central Retinal Vein Occlusion →
Sponsor
Shahid Beheshti University of Medical Sciences
Who can join
Eligibility, any sex, with Central Retinal Vein Occlusion.
What's being measured
Primary outcomes are the specific endpoints the trial is designed to prove or disprove.
-
Visual acuity
Time frame: 6 months
Sponsor's own description
This randomized clinical trial is conducted to evaluate the effect of three intravitreal injections of bevasizumab versus two intravitreal injections of triamcinolone in acute central retinal vein occlusion. The outcomes are visual acuity and central macular thickness. The follow-up time is 6 months.
Publications & conference data
2 peer-reviewed publications reference this trial (live from Europe PMC):
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A systematic review and meta-analysis of the effect of intravitreal VEGF inhibitors on cardiorenal outcomes.
Lees JS, Dobbin SJH, Elyan BMP, Gilmour DF, et al · · 2023 · cited 12× · PMID 36318455 · DOI 10.1093/ndt/gfac305 -
The efficacy and safety of intraocular anti-VEGF injections versus anti-VEGF combined with steroids or steroid monotherapy for macular edema secondary to retinal vein occlusion: a systematic review and meta-analysis of randomized controlled trials.
Cai H, Tian M, Huang Z, Wang B. · · 2025 · PMID 41601793 · DOI 10.3389/fmed.2025.1727801
Verify or expand the search:
- PubMed search for NCT01178697
- Europe PMC full search
- ASCO Meeting Library
- ESMO Meeting Library
- bioRxiv preprints
- medRxiv preprints
- Google Scholar
Related trials
Other recruiting trials for Central Retinal Vein Occlusion
Currently open trials in the same condition.
- NCT05476926 — A Real-World Study to Gain Clinical Insights Into Roche Ophthalmology Products · active not recruiting
Other Shahid Beheshti University of Medical Sciences trials
Trials by the same sponsor.
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- NCT07408492 — Impact of AI-Based Research Training on Nursing Students · NA · not yet recruiting
- NCT07176663 — Efficacy and Safety of Tirzepatide (Spartina) in Chronic Kidney Failure · NA · not yet recruiting
- NCT07291622 — Synchrony-Optimized Non-Invasive Ventilation Education Program and ICU Patients · NA · not yet recruiting
Verify against primary sources
- ClinicalTrials.gov — authoritative US registry record
- WHO ICTRP — international registry index
- EU Clinical Trials Register
- Sponsor press releases (Google)
- Trial protocol + status: ClinicalTrials.gov NCT01178697 (US National Library of Medicine, public domain)
- Publications: Europe PMC API search by NCT ID, retrieved 10 June 2026
- Drug + disease cross-links: matched in real time against Drug Landscape's normalised drug + company + condition tables
- Sponsor: as reported to ClinicalTrials.gov by Shahid Beheshti University of Medical Sciences
- Last refreshed: 9 August 2010
Drug Landscape aggregates and links these public records for informational use only. Always verify against the primary source before clinical or regulatory decisions. Canonical URL: https://druglandscape.com/trial/NCT01178697.
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