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NCT01064063: Vanguard
Randomized Controlled Clinical Evaluation to Compare Vanguard Cruciate Retaining and AGC Total Condylar Knee Implants
NA trial testing Vanguard CR in Osteoarthritis in 150 participants. Completed in 10 May 2022.
15 December 2013
Quick facts
| Lead sponsor | Zimmer Biomet |
|---|---|
| Phase | NA |
| Status | Completed |
| Study type | INTERVENTIONAL |
| Allocation | randomized |
| Design | parallel |
| Masking | single |
| Primary purpose | treatment |
| Enrollment | 150 |
| Start date | 15 February 2011 |
| Primary completion | 15 December 2013 |
| Estimated completion | 10 May 2022 |
| Sites | 1 location across United Kingdom |
Drugs / interventions tested
- Vanguard CR
- AGC knee
Conditions studied
- Osteoarthritis — all drugs for Osteoarthritis →
- Rheumatoid Arthritis — all drugs for Rheumatoid Arthritis →
- Traumatic Arthritis — all drugs for Traumatic Arthritis →
Sponsor
Zimmer Biomet — full company profile →
Who can join
18 and older, any sex, with Osteoarthritis or Rheumatoid Arthritis. Patients with the condition only — healthy volunteers not accepted.
Sponsor's own description
This evaluation is being conducted on the relative new knee system, the Vanguard Cruciate Retaining (CR) to evaluate clinical efficacy of the Vanguard CR components.
Publications & conference data
No peer-reviewed publications indexed yet for this trial. Completed trials usually publish results within 12-18 months.
Verify or expand the search:
- PubMed search for NCT01064063
- Europe PMC full search
- ASCO Meeting Library
- ESMO Meeting Library
- bioRxiv preprints
- medRxiv preprints
- Google Scholar
Related trials
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Currently open trials in the same condition.
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- NCT07006714 — Preoperative Correction of Vitamin D Deficiency in Total Joint Arthroplasty (TJA) · Phase 4 · active not recruiting
Other Zimmer Biomet trials
Trials by the same sponsor.
- NCT06287853 — Tapestry Rotator Cuff Repair PMCF · suspended
- NCT06863428 — Mymobility Knee ROM · recruiting
- NCT06920459 — Zimmer Biomet Shoulder Arthroplasty PMCF Study · recruiting
- NCT07009912 — ROSA® Knee System V1.5 Pilot Study · NA · completed
- NCT06615739 — Comprehensive SRS Regenerex Tissue Attachment · active not recruiting
Verify against primary sources
- ClinicalTrials.gov — authoritative US registry record
- WHO ICTRP — international registry index
- EU Clinical Trials Register
- Sponsor press releases (Google)
- Trial protocol + status: ClinicalTrials.gov NCT01064063 (US National Library of Medicine, public domain)
- Drug + disease cross-links: matched in real time against Drug Landscape's normalised drug + company + condition tables
- Sponsor: as reported to ClinicalTrials.gov by Zimmer Biomet
- Last refreshed: 26 November 2025
Drug Landscape aggregates and links these public records for informational use only. Always verify against the primary source before clinical or regulatory decisions. Canonical URL: https://druglandscape.com/trial/NCT01064063.
Primary sources · FDA · ClinicalTrials.gov · EMA · SEC EDGAR · ChEMBL · Wikidata · full sourcing