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NCT01044329: BRVO

Three Injections of Intravitreal Bevasizumab Versus Two Injections of Intravitreal Triamcinolone in the Management of Branch Retinal Vein Occlusion

Status unknown Phase 2 Last updated 6 January 2010
What this trial tests

Phase 2 trial testing Bevacizumab in Branch Retinal Vein Occlusion in 90 participants. Status unknown.

Timeline
1 January 2010
Primary endpoint
1 August 2010
1 December 2010

Quick facts

Lead sponsorShahid Beheshti University of Medical Sciences
PhasePhase 2
StatusStatus unknown
Study typeINTERVENTIONAL
Allocationrandomized
Designparallel
Maskingsingle
Primary purposetreatment
Enrollment90
Start date1 January 2010
Primary completion1 August 2010
Estimated completion1 December 2010
Sites1 location across Iran

Drugs / interventions tested

Conditions studied

Sponsor

Shahid Beheshti University of Medical Sciences

Who can join

Eligibility, any sex, with Branch Retinal Vein Occlusion. Patients with the condition only — healthy volunteers not accepted.

What's being measured

Primary outcomes are the specific endpoints the trial is designed to prove or disprove.

Sponsor's own description

This randomized clinical trial is conducted to evaluate the effect of three intravitreal injections of bevasizumab versus two intravitreal injections of triamcinolone in acute retinal vein occlusion. The outcomes are visual acuity and central macular thickness. The follow-up time is 6 months.

Publications & conference data

2 peer-reviewed publications reference this trial (live from Europe PMC):

  1. Anti-vascular endothelial growth factor for macular oedema secondary to branch retinal vein occlusion.
    Shalchi Z, Mahroo O, Bunce C, Mitry D. · · 2020 · cited 26× · PMID 32633861 · DOI 10.1002/14651858.cd009510.pub3
  2. The efficacy and safety of intraocular anti-VEGF injections versus anti-VEGF combined with steroids or steroid monotherapy for macular edema secondary to retinal vein occlusion: a systematic review and meta-analysis of randomized controlled trials.
    Cai H, Tian M, Huang Z, Wang B. · · 2025 · PMID 41601793 · DOI 10.3389/fmed.2025.1727801

Verify or expand the search:

Other trials of Bevacizumab

Trials testing the same drug.

Other recruiting trials for Branch Retinal Vein Occlusion

Currently open trials in the same condition.

Other Shahid Beheshti University of Medical Sciences trials

Trials by the same sponsor.

Verify against primary sources

Data sources for this page

Drug Landscape aggregates and links these public records for informational use only. Always verify against the primary source before clinical or regulatory decisions. Canonical URL: https://druglandscape.com/trial/NCT01044329.

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