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NCT01038193

Cognitive Dysfunction After Aneurysmal Subarachnoid Haemorrhage

Completed Last updated 21 February 2024
What this trial tests

trial testing Cognitive assessment in Cognitive Dysfunction in 600 participants. Completed in 31 October 2023.

Timeline
1 March 2009
Primary endpoint
31 October 2023
31 October 2023

Quick facts

Lead sponsorChinese University of Hong Kong
StatusCompleted
Study typeOBSERVATIONAL
Enrollment600
Start date1 March 2009
Primary completion31 October 2023
Estimated completion31 October 2023
Sites1 location across China

Drugs / interventions tested

Conditions studied

Sponsor

Chinese University of Hong Kong

Who can join

Adults 21 to 75, any sex, with Cognitive Dysfunction. Patients with the condition only — healthy volunteers not accepted.

Sponsor's own description

This is a longitudinal, multi-center, prospective study of aneurysmal subarachnoid haemorrhage patients in neurosurgical units in Hong Kong.

Publications & conference data

8 peer-reviewed publications reference this trial (live from Europe PMC):

  1. Evaluation of cognitive impairment by the Montreal cognitive assessment in patients with aneurysmal subarachnoid haemorrhage: prevalence, risk factors and correlations with 3 month outcomes.
    Wong GK, Lam S, Ngai K, Wong A, et al · · 2012 · cited 79× · PMID 22851612 · DOI 10.1136/jnnp-2012-302217
  2. Comparison of montreal cognitive assessment and mini-mental state examination in evaluating cognitive domain deficit following aneurysmal subarachnoid haemorrhage.
    Wong GK, Lam SW, Wong A, Ngai K, et al · · 2013 · cited 45× · PMID 23573223 · DOI 10.1371/journal.pone.0059946
  3. Cognitive domain deficits in patients with aneurysmal subarachnoid haemorrhage at 1 year.
    Wong GK, Lam SW, Ngai K, Wong A, et al · · 2013 · cited 37× · PMID 23606736 · DOI 10.1136/jnnp-2012-304517
  4. Early MoCA-assessed cognitive impairment after aneurysmal subarachnoid hemorrhage and relationship to 1-year functional outcome.
    Wong GK, Lam SW, Wong A, Mok V, et al · · 2014 · cited 32× · PMID 24323708 · DOI 10.1007/s12975-013-0284-z
  5. MoCA-assessed cognitive function and excellent outcome after aneurysmal subarachnoid hemorrhage at 1 year.
    Wong GK, Lam SW, Wong A, Lai M, et al · · 2014 · cited 30× · PMID 24471651 · DOI 10.1111/ene.12363
  6. Development of a short form of Stroke-Specific Quality of Life Scale for patients after aneurysmal subarachnoid hemorrhage.
    Wong GK, Lam SW, Ngai K, Wong A, et al · · 2013 · cited 29× · PMID 24120271 · DOI 10.1016/j.jns.2013.09.033
  7. Cognitive outcome in acute simvastatin treatment for aneurysmal subarachnoid hemorrhage: A propensity matched analysis.
    Wong GK, Wong A, Zee BC, Poon WS, et al · · 2015 · cited 12× · PMID 26285662 · DOI 10.1016/j.jns.2015.08.013
  8. Early Cognitive Domain Deficits in Patients with Aneurysmal Subarachnoid Hemorrhage Correlate with Functional Status.
    Wong GK, Lam SW, Wong A, Ngai K, et al · · 2016 · cited 8× · PMID 27165892 · DOI 10.1007/978-3-319-22533-3_26

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