Last reviewed · How we verify
NCT06354790: LAMA2
Natural History Study of Children With LAMA2-related Dystrophies
trial testing Motor evaluations in Merosin Deficient Congenital Muscular Dystrophy in 40 participants. Currently enrolling.
4 December 2027
Quick facts
| Lead sponsor | Institut de Myologie, France |
|---|---|
| Status | Recruiting now |
| Study type | OBSERVATIONAL |
| Enrollment | 40 |
| Start date | 5 December 2024 |
| Primary completion | 4 December 2027 |
| Estimated completion | 31 December 2027 |
| Sites | 4 locations across France |
Drugs / interventions tested
- Motor evaluations
- Cognitive assessment
- Pulmonary function test
- Cardiac evaluation
- Quality of life
- Spine X Ray
- Muscular MRI
- Biomarkers collection and analysis
Conditions studied
- Merosin Deficient Congenital Muscular Dystrophy — all drugs for Merosin Deficient Congenital Muscular Dystrophy →
Sponsor
Institut de Myologie, France — full company profile →
Who can join
Adults 2 to 15, any sex, with Merosin Deficient Congenital Muscular Dystrophy. Patients with the condition only — healthy volunteers not accepted.
Sponsor's own description
The goal of this natural history study is to characterize the disease course, characteristics in paediatric population of LAMA2-RD (related dystrophies) patients. The aim of the study is to establish a well-described cohort of patients in France with LAMA2-RD for prospective follow-up and recruitment for future clinical trials. Participants will be follow up during a two years period regarding exhaustive aspects of the pathology: * Muscular function * Respiratory function * Cognitive phenotyping * Quality of life * Growth parameters * Biomarkers
Publications & conference data
No peer-reviewed publications indexed yet for this trial.
Verify or expand the search:
- PubMed search for NCT06354790
- Europe PMC full search
- ASCO Meeting Library
- ESMO Meeting Library
- bioRxiv preprints
- medRxiv preprints
- Google Scholar
Related trials
Other recruiting trials for Merosin Deficient Congenital Muscular Dystrophy
Currently open trials in the same condition.
- NCT06924125 — Spanish Natural History Study for LAMA2 Muscular Dystrophy · recruiting
Other Institut de Myologie, France trials
Trials by the same sponsor.
- NCT07321977 — Assessment of a Portable Digital Device for Quantified Analysis of Markerless Walking in Volunteers With Neuromuscular D · NA · recruiting
- NCT07321990 — Study of the Reproducibility of the French Version of the Modified SMAFRS Scale · recruiting
- NCT05839145 — Home Monitoring of Adult Patients With SMA: a Pilot Multicenter Validation Study · NA · unknown
- NCT05798325 — Feasibility, Validation and Application of Digital Tools for the Follow-up of Neuromuscular Patient Mobility in Daily Li · NA · unknown
- NCT05265351 — Ultrafast Ultrasound for the Functional Assessment of the Diaphragm · NA · unknown
Verify against primary sources
- ClinicalTrials.gov — authoritative US registry record
- WHO ICTRP — international registry index
- EU Clinical Trials Register
- Sponsor press releases (Google)
- Trial protocol + status: ClinicalTrials.gov NCT06354790 (US National Library of Medicine, public domain)
- Drug + disease cross-links: matched in real time against Drug Landscape's normalised drug + company + condition tables
- Sponsor: as reported to ClinicalTrials.gov by Institut de Myologie, France
- Last refreshed: 12 December 2024
Drug Landscape aggregates and links these public records for informational use only. Always verify against the primary source before clinical or regulatory decisions. Canonical URL: https://druglandscape.com/trial/NCT06354790.
Primary sources · FDA · ClinicalTrials.gov · EMA · SEC EDGAR · ChEMBL · Wikidata · full sourcing