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NCT00958425
Intraoperative Hyaluronic Acid Gel Injection for Improvement of Scar Quality Following Reduction Mammaplasty
Phase 3 trial testing Hyaluronic acid gel in Cicatrix. Withdrawn.
1 January 2014
Quick facts
| Lead sponsor | Nova Scotia Health Authority |
|---|---|
| Phase | Phase 3 |
| Status | Withdrawn |
| Study type | INTERVENTIONAL |
| Allocation | randomized |
| Design | parallel |
| Masking | quadruple |
| Primary purpose | treatment |
| Start date | 1 January 2014 |
| Primary completion | 1 January 2014 |
| Estimated completion | 1 January 2014 |
Drugs / interventions tested
- Hyaluronic acid gel
- Saline
Conditions studied
- Cicatrix — all drugs for Cicatrix →
Sponsor
Nova Scotia Health Authority — full company profile →
Who can join
18 and older, female only, with Cicatrix. Patients with the condition only — healthy volunteers not accepted.
Sponsor's own description
The purpose of this study is to determine the efficacy of hyaluronic acid gel injections compared to saline injections in improving scar quality in patients undergoing breast reduction surgery. Hyaluronic acid has been implicated in scarless fetal healing, and the investigators therefore hypothesize that injections of hyaluronic acid gel into breast reduction incisions will improve their appearance compared to injections of saline.
Publications & conference data
1 peer-reviewed publication reference this trial (live from Europe PMC):
-
Modelling and targeting mechanical forces in organ fibrosis.
Mascharak S, Guo JL, Griffin M, Berry CE, et al · · 2024 · cited 23× · PMID 39552705 · DOI 10.1038/s44222-023-00144-3
Verify or expand the search:
- PubMed search for NCT00958425
- Europe PMC full search
- ASCO Meeting Library
- ESMO Meeting Library
- bioRxiv preprints
- medRxiv preprints
- Google Scholar
Related trials
Other trials of Hyaluronic acid gel
Trials testing the same drug.
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- NCT05953896 — Efficacy of HA Gel Injection Versus Multilayer (L-PRF) in the Interdental Papilla Reconstruction · NA · completed
- NCT04869306 — Effect of Hyaluronic Acid on Tissue Healing After Removal of Impacted Mandibular Third Molars (LM3) · NA · unknown
- NCT04853589 — Effect of Hyaluronic Acid on the Therapy of Alveolar Osteitis · NA · unknown
Other recruiting trials for Cicatrix
Currently open trials in the same condition.
- NCT06122090 — Treatment of Hypopigmented Scars With Bimatoprost · Phase 2 · recruiting
Other Nova Scotia Health Authority trials
Trials by the same sponsor.
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- NCT06575621 — Knee-hip Surgery Wait-list Support Program · NA · not yet recruiting
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- NCT07239999 — Comparing Spinal Anesthesia With 1% Chloroprocaine Versus 1% Mepivacaine in Patients Undergoing Outpatient Primary Total · Phase 4 · not yet recruiting
Verify against primary sources
- ClinicalTrials.gov — authoritative US registry record
- WHO ICTRP — international registry index
- EU Clinical Trials Register
- Sponsor press releases (Google)
- Trial protocol + status: ClinicalTrials.gov NCT00958425 (US National Library of Medicine, public domain)
- Publications: Europe PMC API search by NCT ID, retrieved 10 June 2026
- Drug + disease cross-links: matched in real time against Drug Landscape's normalised drug + company + condition tables
- Sponsor: as reported to ClinicalTrials.gov by Nova Scotia Health Authority
- Last refreshed: 21 August 2024
Drug Landscape aggregates and links these public records for informational use only. Always verify against the primary source before clinical or regulatory decisions. Canonical URL: https://druglandscape.com/trial/NCT00958425.
Primary sources · FDA · ClinicalTrials.gov · EMA · SEC EDGAR · ChEMBL · Wikidata · full sourcing