NCT00879853

Trial of Mental Health Treatment for Darfur Refugees in Cairo

Completed NA Last updated 8 November 2023

What this trial tests

NA trial testing Interpersonal Therapy in Post-Traumatic Stress Disorder. Completed.

Quick facts

Lead sponsor	University of California, San Francisco
Phase	NA
Status	Completed
Study type	INTERVENTIONAL
Sites	1 location across Egypt

Drugs / interventions tested

• Interpersonal Therapy

Conditions studied

• Post-Traumatic Stress Disorder — all drugs for Post-Traumatic Stress Disorder →
• Depression — all drugs for Depression →
• Anger — all drugs for Anger →
• Domestic Violence — all drugs for Domestic Violence →

Sponsor

University of California, San Francisco

Who can join

18 and older, any sex, with Post-Traumatic Stress Disorder or Depression. Patients with the condition only — healthy volunteers not accepted.

Sponsor's own description

The enormous global burden of mental illness has been estimated through the publication of the Global Burden of Disease Study, adding momentum to refugee mental health studies (1,2). As research confirms that high levels of Posttraumatic Stress Disorder (PTSD) and depression occur in post-conflict settings, it is essential to develop effective treatment for psychological trauma in refugee populations recovering from mass violence (3-4). PTSD and depression are risk factors for anger, interpersonal discord and violence, not only among those who have trauma and depression, but also among their spouses and children (5-9). This "infectious" model of trauma/violence is critically important in the setting of ethnic conflict, as increased levels of interpersonal violence within the afflicted community hinder its recovery and fuel future cycles of conflict. To date, there has been little research on the interpersonal effects of trauma among refugee populations. The proposed research is a pilot and randomized controlled trial of "Interpersonal Therapy" (IPT) for Sudanese refugees living in Cairo. IPT, a very effective therapy for depression, has been adapted for PTSD treatment and sub-Saharan Africa settings (10-12). Measures will evaluate success of the treatment not only in terms of individual PTSD and depression symptoms, but also with respect to interpersonal conflict. Hypotheses: (1) After IPT intervention, Sudanese refugees will have lower levels of depression and trauma symptoms compared to wait list controls (2) After IPT intervention, Sudanese refugees will have lower levels of interpersonal violence compared to wait list controls.

Publications & conference data

No peer-reviewed publications indexed yet for this trial. Completed trials usually publish results within 12-18 months.