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NCT00751218
A Comparative Double-Blind, Double- Dummy Study of Desloratadine (DL) 5 MG Once Daily, Cetirizine 10 MG Once Daily, and Placebo Once Daily in Patients With Chronic Idiopathic Urticaria (Study P03735)
Phase 4 trial testing desloratadine in Urticaria in 174 participants. Completed in 24 May 2005.
24 May 2005
Quick facts
| Lead sponsor | Organon and Co |
|---|---|
| Phase | Phase 4 |
| Status | Completed |
| Study type | INTERVENTIONAL |
| Allocation | randomized |
| Design | parallel |
| Masking | triple |
| Primary purpose | treatment |
| Enrollment | 174 |
| Start date | 6 May 2004 |
| Primary completion | 24 May 2005 |
| Estimated completion | 24 May 2005 |
Drugs / interventions tested
- desloratadine (desloratadine) — full drug profile →
- placebo
- cetirizine (cetirizine) — full drug profile →
Conditions studied
- Urticaria — all drugs for Urticaria →
Sponsor
Organon and Co — full company profile →
Who can join
Adults 12 to 70, any sex, with Urticaria. Patients with the condition only — healthy volunteers not accepted.
Sponsor's own description
This was a randomized, double-blind, parallel-group, multicenter study that used both an active control (cetirizine) and a placebo control to evaluate desloratadine 5 mg once daily during a 28-day treatment period. The active treatments and placebo were allocated in a 2:2:1 ratio.
Publications & conference data
1 peer-reviewed publication reference this trial (live from Europe PMC):
-
H1-antihistamines for chronic spontaneous urticaria.
Sharma M, Bennett C, Cohen SN, Carter B. · · 2014 · cited 22× · PMID 25397904 · DOI 10.1002/14651858.cd006137.pub2
Verify or expand the search:
- PubMed search for NCT00751218
- Europe PMC full search
- ASCO Meeting Library
- ESMO Meeting Library
- bioRxiv preprints
- medRxiv preprints
- Google Scholar
Related trials
Other trials of desloratadine
Trials testing the same drug.
- NCT00311844 — A Study of the Effects of Desloratadine on Conjunctival Allergen Challenge-induced Ocular Signs and Symptoms (Study P042 · Phase 4 · completed
- NCT00783211 — Efficacy and Safety of Desloratadine vs. Fexofenadine 180 mg. vs. Placebo for Treating Seasonal Allergic Rhinitis (SAR)( · Phase 4 · completed
- NCT00783146 — Efficacy and Safety of Desloratadine vs. Fexofenadine 180 mg. vs. Placebo for Treating Seasonal Allergic Rhinitis (SAR) · Phase 4 · completed
- NCT00789152 — The Effect of Desloratadine and Levocetirizine on Nasal Obstruction (Study P03609) · Phase 3 · completed
- NCT00783354 — A Comparison of Aerius Continuous Treatment Versus Aerius PRN for Chronic Idiopathic Urticaria (Study P03147) · Phase 4 · completed
Other Organon and Co trials
Trials by the same sponsor.
- NCT05761444 — Effectiveness and Safety Study of Early add-on of Ezetimibe With Atorvastatin in Very High-risk Patients · Phase 4 · completed
- NCT05789576 — A Study to Investigate Efficacy and Safety of VTAMA® (Tapinarof) Cream, 1% in Plaque Psoriasis in the Head and Neck Regi · Phase 4 · completed
- NCT05680740 — A Study to Investigate Efficacy and Safety of VTAMA (Tapinarof) Cream, 1% in Intertriginous Plaque Psoriasis · Phase 4 · completed
- NCT05560646 — A Study to Investigate Efficacy and Safety of OG-6219 BID in 3 Dose Levels Compared With Placebo in Participants Aged 18 · Phase 2 · completed
- NCT05264506 — Contraceptive Efficacy and Safety of NOMAC-E2 Combined Oral Contraceptive · Phase 3 · terminated
Verify against primary sources
- ClinicalTrials.gov — authoritative US registry record
- WHO ICTRP — international registry index
- EU Clinical Trials Register
- Sponsor press releases (Google)
- Trial protocol + status: ClinicalTrials.gov NCT00751218 (US National Library of Medicine, public domain)
- Publications: Europe PMC API search by NCT ID, retrieved 10 June 2026
- Drug + disease cross-links: matched in real time against Drug Landscape's normalised drug + company + condition tables
- Sponsor: as reported to ClinicalTrials.gov by Organon and Co
- Last refreshed: 15 August 2024
Drug Landscape aggregates and links these public records for informational use only. Always verify against the primary source before clinical or regulatory decisions. Canonical URL: https://druglandscape.com/trial/NCT00751218.
Primary sources · FDA · ClinicalTrials.gov · EMA · SEC EDGAR · ChEMBL · Wikidata · full sourcing