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NCT00731185
Mometasone Furoate Nasal Spray for Treatment of Nasal Polyposis After Surgery (Study P03218)
Phase 3 trial testing Mometasone Furoate Nasal Spray in Nasal Polyps in 162 participants. Completed in 1 September 2005.
1 September 2005
Quick facts
| Lead sponsor | Organon and Co |
|---|---|
| Phase | Phase 3 |
| Status | Completed |
| Study type | INTERVENTIONAL |
| Allocation | randomized |
| Design | parallel |
| Masking | quadruple |
| Primary purpose | treatment |
| Enrollment | 162 |
| Start date | 1 September 2003 |
| Primary completion | 1 September 2005 |
| Estimated completion | 1 September 2005 |
Drugs / interventions tested
- Mometasone Furoate Nasal Spray — full drug profile →
- Placebo
Conditions studied
- Nasal Polyps — all drugs for Nasal Polyps →
Sponsor
Organon and Co — full company profile →
Who can join
18 and older, any sex, with Nasal Polyps. Patients with the condition only — healthy volunteers not accepted.
Sponsor's own description
This study was conducted to evaluate the effectiveness of mometasone nasal spray in preventing polyp relapse/symptom worsening in patients after surgical treatment of nasal polyps. Patients who met Screening eligibility underwent endoscopic sino-nasal surgery (FESS) on visit 2. Mometasone nasal spray or placebo was started about 2 weeks after surgery and continued for up to 24 weeks or until relapse.
Publications & conference data
1 peer-reviewed publication reference this trial (live from Europe PMC):
-
Use of mometasone furoate to prevent polyp relapse after endoscopic sinus surgery.
Stjärne P, Olsson P, Alenius M. · · 2009 · cited 68× · PMID 19289710 · DOI 10.1001/archoto.2009.2
Verify or expand the search:
- PubMed search for NCT00731185
- Europe PMC full search
- ASCO Meeting Library
- ESMO Meeting Library
- bioRxiv preprints
- medRxiv preprints
- Google Scholar
Related trials
Other trials of Mometasone Furoate Nasal Spray
Trials testing the same drug.
- NCT03614923 — Etokimab in Adults With Chronic Rhinosinusitis With Nasal Polyps (CRSwNP) · Phase 2 · completed
- NCT03451318 — Multi-disciplinary Diagnosis and Treatment Process and Evaluation System for Children With Sleep Disordered Breathing an · NA · unknown
- NCT00783458 — Single Dose Crossover Study of Patient Preference for Unscented Nasonex® Nasal Spray Versus Scented Flonase® Nasal Spray · Phase 4 · completed
- NCT00817050 — Single Dose Crossover Study of Patient Preference for Unscented Nasonex® Nasal Spray Versus Scented Flonase® Nasal Spray · Phase 4 · completed
Other recruiting trials for Nasal Polyps
Currently open trials in the same condition.
- NCT07245329 — Effect of Full-House ESS With Nasopharyngeal Lymphoid Tissue Ablation on Nasal Polyps · NA · recruiting
- NCT07268313 — Complete Remission After Treatment With Biologics for Nasal Polyps · Phase 4 · recruiting
- NCT05575037 — Mechanisms of Benefit of IL4RA Inhibition in Aspirin-Exacerbated Respiratory Disease · Phase 2 · active not recruiting
- NCT05094570 — Interleukin-4Ra Blockade by Dupilumab Decreases Staphylococcus Colonization and Increases Microbial Diversity in CRSwNP · Phase 4 · recruiting
- NCT05287841 — Does Batten Grafting Improve Nasal Outcomes in Septoplasty and Turbinate Reduction? · NA · recruiting
Other Organon and Co trials
Trials by the same sponsor.
- NCT05761444 — Effectiveness and Safety Study of Early add-on of Ezetimibe With Atorvastatin in Very High-risk Patients · Phase 4 · completed
- NCT05789576 — A Study to Investigate Efficacy and Safety of VTAMA® (Tapinarof) Cream, 1% in Plaque Psoriasis in the Head and Neck Regi · Phase 4 · completed
- NCT05680740 — A Study to Investigate Efficacy and Safety of VTAMA (Tapinarof) Cream, 1% in Intertriginous Plaque Psoriasis · Phase 4 · completed
- NCT05560646 — A Study to Investigate Efficacy and Safety of OG-6219 BID in 3 Dose Levels Compared With Placebo in Participants Aged 18 · Phase 2 · completed
- NCT05264506 — Contraceptive Efficacy and Safety of NOMAC-E2 Combined Oral Contraceptive · Phase 3 · terminated
Verify against primary sources
- ClinicalTrials.gov — authoritative US registry record
- WHO ICTRP — international registry index
- EU Clinical Trials Register
- Sponsor press releases (Google)
- Trial protocol + status: ClinicalTrials.gov NCT00731185 (US National Library of Medicine, public domain)
- Publications: Europe PMC API search by NCT ID, retrieved 10 June 2026
- Drug + disease cross-links: matched in real time against Drug Landscape's normalised drug + company + condition tables
- Sponsor: as reported to ClinicalTrials.gov by Organon and Co
- Last refreshed: 15 August 2024
Drug Landscape aggregates and links these public records for informational use only. Always verify against the primary source before clinical or regulatory decisions. Canonical URL: https://druglandscape.com/trial/NCT00731185.
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