Last reviewed · How we verify
NCT00691717
A Study of the Safety and IOP-Lowering Efficacy of Anecortave Acetate in Patients With Open-Angle Glaucoma or Ocular Hypertension
Phase 2/Phase 3 trial testing Anecortave Acetate Sterile Suspension, 30 mg/mL in Open-angle Glaucoma in 201 participants. Completed in 1 September 2009.
1 September 2009
Quick facts
| Lead sponsor | Alcon Research |
|---|---|
| Phase | Phase 2/Phase 3 |
| Status | Completed |
| Study type | INTERVENTIONAL |
| Allocation | randomized |
| Design | parallel |
| Masking | triple |
| Primary purpose | treatment |
| Enrollment | 201 |
| Start date | 1 June 2008 |
| Primary completion | 1 September 2009 |
| Estimated completion | 1 September 2009 |
| Sites | 1 location across United States |
Drugs / interventions tested
- Anecortave Acetate Sterile Suspension, 30 mg/mL — full drug profile →
- Anecortave Acetate Sterile Suspension, 60 mg/mL — full drug profile →
- Anecortave Acetate Sterile Suspension, 75 mg/mL — full drug profile →
- Anecortave Acetate Vehicle
Conditions studied
- Open-angle Glaucoma — all drugs for Open-angle Glaucoma →
- Oular Hypertension — all drugs for Oular Hypertension →
Sponsor
Alcon Research — full company profile →
Who can join
18 and older, any sex, with Open-angle Glaucoma or Oular Hypertension. Patients with the condition only — healthy volunteers not accepted.
What's being measured
Primary outcomes are the specific endpoints the trial is designed to prove or disprove.
-
Mean Intraocular Pressure at 8 am
Time frame: Up to 6 months
Sponsor's own description
The purpose of this study was to evaluate the safety and intraocular-lowering efficacy of anecortave acetate depot when administered by anterior juxtascleral depot (AJD) for the treatment of elevated intraocular pressure (IOP) in patients with open-angle glaucoma or ocular hypertension.
Publications & conference data
No peer-reviewed publications indexed yet for this trial. Completed trials usually publish results within 12-18 months.
Verify or expand the search:
- PubMed search for NCT00691717
- Europe PMC full search
- ASCO Meeting Library
- ESMO Meeting Library
- bioRxiv preprints
- medRxiv preprints
- Google Scholar
Related trials
Other recruiting trials for Open-angle Glaucoma
Currently open trials in the same condition.
- NCT06885827 — Vitamin Mix (B6, B9, B12, And Choline) For Glaucoma Patients · NA · recruiting
- NCT06267274 — A Randomized, Double-blind, Parallel-group, Two-arm, Multiple Dose, Multicenter, Bioequivalence Study With Clinical Endp · Phase 1 · recruiting
- NCT05822245 — A Study of PER-001 in Participants With Open-Angle Glaucoma · Phase 1, PHASE2 · active not recruiting
- NCT06741774 — Efficacy and Safety of Trabecular Meshwork Microstent Drainage System ( MicroCOGO ) · NA · active not recruiting
Other Alcon Research trials
Trials by the same sponsor.
- NCT06884202 — Evaluation of Delefilcon A Contact Lenses · NA · completed
- NCT06784063 — Visual Performance With Clareon® Vivity® Intraocular Lenses (IOLs) · NA · completed
- NCT06571656 — Evaluation of the Safety and Tolerability of Ocular Lubricants · NA · terminated
- NCT06660290 — A Study to Evaluate 0.003% AR-15512 Safety and Drop Attributes · Phase 3 · completed
- NCT06483113 — DAILIES TOTAL1® Soft Contact Lenses - Post-Market Clinical Follow-up Study · terminated
Verify against primary sources
- ClinicalTrials.gov — authoritative US registry record
- WHO ICTRP — international registry index
- EU Clinical Trials Register
- Sponsor press releases (Google)
- Trial protocol + status: ClinicalTrials.gov NCT00691717 (US National Library of Medicine, public domain)
- Drug + disease cross-links: matched in real time against Drug Landscape's normalised drug + company + condition tables
- Sponsor: as reported to ClinicalTrials.gov by Alcon Research
- Last refreshed: 27 November 2012
Drug Landscape aggregates and links these public records for informational use only. Always verify against the primary source before clinical or regulatory decisions. Canonical URL: https://druglandscape.com/trial/NCT00691717.
Primary sources · FDA · ClinicalTrials.gov · EMA · SEC EDGAR · ChEMBL · Wikidata · full sourcing