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NCT00691626
Cognitive Behavioral Therapy (CBT) for Nightmares in Operation Enduring Freedom/Operation Iraqi Freedom (OEF/OIF) Veterans
NA trial testing CBT for Insomnia plus Imagery Rehearsal in Posttraumatic Stress Disorder in 108 participants. Completed in 31 December 2019.
1 January 2015
Quick facts
| Lead sponsor | VA Office of Research and Development |
|---|---|
| Phase | NA |
| Status | Completed |
| Study type | INTERVENTIONAL |
| Allocation | randomized |
| Design | parallel |
| Masking | single |
| Primary purpose | treatment |
| Enrollment | 108 |
| Start date | 1 April 2009 |
| Primary completion | 1 January 2015 |
| Estimated completion | 31 December 2019 |
| Sites | 1 location across United States |
Drugs / interventions tested
- CBT for Insomnia plus Imagery Rehearsal
- CBT for Insomnia plus psychoeducation
Conditions studied
- Posttraumatic Stress Disorder — all drugs for Posttraumatic Stress Disorder →
- Sleep Disorders — all drugs for Sleep Disorders →
- Nightmares — all drugs for Nightmares →
Sponsor
VA Office of Research and Development — full company profile →
Who can join
Adults 18 to 60, any sex, with Posttraumatic Stress Disorder or Sleep Disorders. Patients with the condition only — healthy volunteers not accepted.
Sponsor's own description
The purpose of this study is to compare the effectiveness of two talk therapies for OEF/OIF Veterans at the Michael J. Crescenz and the West Haven VA Medical Centers. Participants will randomly receive one of two individual treatments intended to improve the sleep disturbance and nightmares of returning Veterans.
Publications & conference data
3 peer-reviewed publications reference this trial (live from Europe PMC):
-
Treating nightmares and insomnia in posttraumatic stress disorder: a review of current evidence.
Nappi CM, Drummond SP, Hall JM. · · 2012 · cited 80× · PMID 21396945 · DOI 10.1016/j.neuropharm.2011.02.029 -
Verbal memory functioning moderates psychotherapy treatment response for PTSD-Related nightmares.
Scott JC, Harb G, Brownlow JA, Greene J, et al · · 2017 · cited 36× · PMID 28110112 · DOI 10.1016/j.brat.2017.01.004 -
Randomized Controlled Trial of Imagery Rehearsal for Posttraumatic Nightmares in Combat Veterans.
Harb GC, Cook JM, Phelps AJ, Gehrman PR, et al · · 2019 · cited 29× · PMID 31053215 · DOI 10.5664/jcsm.7770
Verify or expand the search:
- PubMed search for NCT00691626
- Europe PMC full search
- ASCO Meeting Library
- ESMO Meeting Library
- bioRxiv preprints
- medRxiv preprints
- Google Scholar
Related trials
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Other VA Office of Research and Development trials
Trials by the same sponsor.
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- NCT06746727 — The Development of a Transdiagnostic Intervention to Improve Social Functioning and Intimate Relationships Among Veteran · NA · not yet recruiting
- NCT07362576 — Perinatal Peer Support for Veterans With Serious Mental Illness · NA · not yet recruiting
- NCT06766331 — Integrated Care Versus Usual Care for Opioid Use Disorder and Infectious Diseases in Veterans · NA · not yet recruiting
- NCT07397195 — ACT for Veterans With IBD and Mental Health Challenges · NA · not yet recruiting
Verify against primary sources
- ClinicalTrials.gov — authoritative US registry record
- WHO ICTRP — international registry index
- EU Clinical Trials Register
- Sponsor press releases (Google)
- Trial protocol + status: ClinicalTrials.gov NCT00691626 (US National Library of Medicine, public domain)
- Publications: Europe PMC API search by NCT ID, retrieved 10 June 2026
- Drug + disease cross-links: matched in real time against Drug Landscape's normalised drug + company + condition tables
- Sponsor: as reported to ClinicalTrials.gov by VA Office of Research and Development
- Last refreshed: 31 January 2020
Drug Landscape aggregates and links these public records for informational use only. Always verify against the primary source before clinical or regulatory decisions. Canonical URL: https://druglandscape.com/trial/NCT00691626.
Primary sources · FDA · ClinicalTrials.gov · EMA · SEC EDGAR · ChEMBL · Wikidata · full sourcing