Who is sponsoring NCT00546598?

NCT00546598 is sponsored by DePuy Orthopaedics.

What drugs are being tested in NCT00546598?

Interventions in NCT00546598: Total hip replacement/arthroplasty.

What condition does NCT00546598 study?

NCT00546598 studies Non-inflammatory Joint Disease, Osteoarthritis, Avascular Necrosis, Congenital Hip Dysplasia, Post-traumatic Arthritis.

Is NCT00546598 still recruiting?

NCT00546598 is currently terminated. Last updated 30 November 2021.

Last reviewed 2021-11-30 · How we verify

NCT00546598

Name: Drug Landscape Pharmaceutical Database
Creator: Drug Landscape
Published: 2026-01-01
License: https://creativecommons.org/licenses/by/4.0/

Post-approval Study of the DURALOC® Option Ceramic-on-Ceramic Hip Prosthesis System

Terminated Phase 4 Last updated 30 November 2021

What this trial tests

Phase 4 trial testing Total hip replacement/arthroplasty in Non-inflammatory Joint Disease in 106 participants. Terminated before completion.

Timeline

1 January 2006

Primary endpoint
1 April 2014

1 April 2014

Quick facts

Lead sponsor	DePuy Orthopaedics
Phase	Phase 4
Status	Terminated
Study type	INTERVENTIONAL
Allocation	na
Design	single group
Masking	none
Primary purpose	treatment
Enrollment	106
Start date	1 January 2006
Primary completion	1 April 2014
Estimated completion	1 April 2014
Sites	6 locations across United States

Drugs / interventions tested

Total hip replacement/arthroplasty

Conditions studied

Non-inflammatory Joint Disease — all drugs for Non-inflammatory Joint Disease →
Osteoarthritis — all drugs for Osteoarthritis →
Avascular Necrosis — all drugs for Avascular Necrosis →
Congenital Hip Dysplasia — all drugs for Congenital Hip Dysplasia →

Sponsor

DePuy Orthopaedics — full company profile →

Who can join

Adults 21 to 80, any sex, with Non-inflammatory Joint Disease or Osteoarthritis. Patients with the condition only — healthy volunteers not accepted.

Sponsor's own description

This study is being conducted to gather medium and long-term information regarding the performance and safety of the commercially available DURALOC® Option Ceramic-on-Ceramic Hip Prosthesis System.

Publications & conference data

No peer-reviewed publications indexed yet for this trial.

Verify or expand the search:

Other DePuy Orthopaedics trials

Trials by the same sponsor.

NCT06631638 — EMPHASYS Cup Positioning in THA With Non-Invasive Navigation (Velys Hip Navigation (VHN)) · NA · recruiting
NCT06323980 — INHANCE Stemless Reverse Shoulder IDE · NA · recruiting
NCT05357664 — PINNACLE® DM RSA Study · NA · terminated
NCT04630262 — ATTUNE Cementless FB Tibial Base Clinical Study · NA · terminated
NCT04730271 — Comparison of Alignment Achieved Using the VELYS Robotic-Assisted Solution Versus Manual Instrumentation in Total Knee A · NA · completed

Verify against primary sources

ClinicalTrials.gov — authoritative US registry record
WHO ICTRP — international registry index
EU Clinical Trials Register
Sponsor press releases (Google)

Data sources for this page

Trial protocol + status: ClinicalTrials.gov NCT00546598 (US National Library of Medicine, public domain)
Drug + disease cross-links: matched in real time against Drug Landscape's normalised drug + company + condition tables
Sponsor: as reported to ClinicalTrials.gov by DePuy Orthopaedics
Last refreshed: 30 November 2021

Drug Landscape aggregates and links these public records for informational use only. Always verify against the primary source before clinical or regulatory decisions. Canonical URL: https://druglandscape.com/trial/NCT00546598.

Primary sources · FDA · ClinicalTrials.gov · EMA · SEC EDGAR · ChEMBL · Wikidata · full sourcing