NCT00520442 is a NA clinical trial of ibuprofen in Fracture, sponsored by Medical College of Wisconsin.

Who is sponsoring NCT00520442?

NCT00520442 is sponsored by Medical College of Wisconsin.

What drugs are being tested in NCT00520442?

Interventions in NCT00520442: ibuprofen, acetamin w codeine.

Is NCT00520442 still recruiting?

NCT00520442 is currently completed. Last updated 6 March 2008.

Last reviewed 2008-03-06 · How we verify

NCT00520442

Name: Drug Landscape Pharmaceutical Database
Creator: Drug Landscape
Published: 2026-01-01
License: https://creativecommons.org/licenses/by/4.0/

Ibuprofen Versus Acetaminophen With Codeine In Acute Pediatric Forearm Fractures

Completed NA Last updated 6 March 2008

What this trial tests

NA trial testing ibuprofen in Fracture in 335 participants. Completed in 1 September 2007.

Timeline

1 September 2003

Primary endpoint
1 September 2007

1 September 2007

Quick facts

Lead sponsor	Medical College of Wisconsin
Phase	NA
Status	Completed
Study type	INTERVENTIONAL
Allocation	randomized
Design	parallel
Masking	quadruple
Primary purpose	treatment
Enrollment	335
Start date	1 September 2003
Primary completion	1 September 2007
Estimated completion	1 September 2007
Sites	1 location across United States

Drugs / interventions tested

ibuprofen (ibuprofen) — full drug profile →
acetamin w codeine — full drug profile →

Conditions studied

Fracture — all drugs for Fracture →

Sponsor

Medical College of Wisconsin

Who can join

Adults 4 to 18, any sex, with Fracture. Healthy volunteers can join.

What's being measured

Primary outcomes are the specific endpoints the trial is designed to prove or disprove.

Change to rescue medication
Time frame: First 72 hours after ED discharge

Sponsor's own description

A clinical trial comparing ibuprofen and acetaminophen with codeine for children after discharge from the emergency department. We hypothesize that Ibuprofen will provide 20% more effective analgesia compared to acetaminophen with codeine in children with uncomplicated forearm fractures.

Publications & conference data

1 peer-reviewed publication reference this trial (live from Europe PMC):

Video Education Intervention in the Emergency Department.
Jacobson N, Coleman KD, Weisman SJ, Drendel AL. · · 2022 · cited 4× · PMID 36602480 · DOI 10.5811/westjem.2022.9.57986

Verify or expand the search:

Other trials of ibuprofen

Trials testing the same drug.

NCT07399184 — Effect of Perioperative IV Ibuprofen on Cerebral Oxygenation and Postoperative Cognition During One-Lung Ventilation · NA · not yet recruiting
NCT06786650 — Comparision of the Analgesic Effects of Intravenous Ibuprofen and Tenoxicam in Acute Migraine Attack · Phase 4 · active not recruiting
NCT06948513 — Effect of Over-the-counter Analgesics on Postoperative Pain · Phase 3 · completed
NCT04429282 — A Multicenter, Randomized, Double-Blind, Placebo-Controlled Trial of Intravenous Ibuprofen 400 and 800 mg Every 6 Hours · Phase 3 · unknown
NCT03952650 — Sanaria PfSPZ Challenge With Pyrimethamine or Chloroquine Chemoprophylaxis Vaccination (PfSPZ-CVac Approach): A Randomiz · Phase 1, PHASE2 · completed

Other recruiting trials for Fracture

Currently open trials in the same condition.

NCT07221019 — Single Shot Exparel vs Catheters in Lower Extremity Trauma · Phase 4 · recruiting
NCT04921865 — Case Series on the Clinical Performance of VA Clavicle and Clavicle Hook Plate 2.7 Systems · recruiting
NCT04947722 — The PREVENT Trial: a Pragmatic Cluster Randomized Controlled Trial of a Multifaceted Fracture Prevention Model for Long- · NA · recruiting
NCT07256405 — Metagenomic Next-Generation Sequencing for the Diagnosis of Fracture-related Infection · active not recruiting
NCT05292001 — Single-dose Intravenous Iron Therapy for Anemia After Orthopaedic Trauma · Phase 4 · recruiting

Other Medical College of Wisconsin trials

Trials by the same sponsor.

NCT07260552 — Rapid Engagement for Solutions to Population and Outcomes Through Networked Dialogue for Coronary Heart Disease · not yet recruiting
NCT06795360 — Weight Changes After Incretin-mimetics · NA · not yet recruiting
NCT07228208 — Role of Endothelial Dysfunction on Exercise Pressor Reflex in Type 2 Diabetes · NA · not yet recruiting
NCT07298460 — Stimulation-based Therapy to Improve Balance in DCM · Phase 1, PHASE2 · not yet recruiting
NCT07434544 — Cardiometabolic Effects of Non-Nutritive Sweeteners (NNS) in Type 1 Diabetes (T1D) · NA · not yet recruiting

Verify against primary sources

ClinicalTrials.gov — authoritative US registry record
WHO ICTRP — international registry index
EU Clinical Trials Register
Sponsor press releases (Google)

Data sources for this page

Trial protocol + status: ClinicalTrials.gov NCT00520442 (US National Library of Medicine, public domain)
Publications: Europe PMC API search by NCT ID, retrieved 10 June 2026
Drug + disease cross-links: matched in real time against Drug Landscape's normalised drug + company + condition tables
Sponsor: as reported to ClinicalTrials.gov by Medical College of Wisconsin
Last refreshed: 6 March 2008

Drug Landscape aggregates and links these public records for informational use only. Always verify against the primary source before clinical or regulatory decisions. Canonical URL: https://druglandscape.com/trial/NCT00520442.

Primary sources · FDA · ClinicalTrials.gov · EMA · SEC EDGAR · ChEMBL · Wikidata · full sourcing