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NCT00504374

Gene Polymorphisms and Symptoms in Lung Cancer Patients

Completed Last updated 4 June 2019
What this trial tests

trial testing Questionnaire in Lung Cancer in 235 participants. Completed in 27 April 2017.

Timeline
13 June 2006
Primary endpoint
27 April 2017
27 April 2017

Quick facts

Lead sponsorM.D. Anderson Cancer Center
StatusCompleted
Study typeOBSERVATIONAL
Enrollment235
Start date13 June 2006
Primary completion27 April 2017
Estimated completion27 April 2017
Sites1 location across United States

Drugs / interventions tested

Conditions studied

Sponsor

M.D. Anderson Cancer Center — full company profile →

Who can join

18 and older, any sex, with Lung Cancer. Patients with the condition only — healthy volunteers not accepted.

Sponsor's own description

Primary Objectives: * Construct a prospective cohort of patients diagnosed with lung cancer and dispositioned for treatment and collect information on symptoms and symptom treatments at baseline and on follow-up. * Develop preliminary statistical models incorporating genetic data (which will be obtained from an existing protocol, CPN 91-001, Margaret Spitz), disease-related variables (e.g., stage of disease, location of tumor), clinical health status (e.g., performance status, comorbid conditions), and sociodemographic characteristics (e.g., age, sex, race) for predicting the risk of severe and persistent symptoms. Analytical aim: To determine if symptoms (e.g., fatigue, depression, lack of appetite) will differ in severity by IL-6 gene polymorphisms (-174G/C, -597G/A, -572G/C, -373An/Tn). This study (NIH-CA109043, Reyes-Gibby, 2004-2009) builds upon an NIH-funded (NIH-CA55769, Spitz, 2003-2008) study of the molecular epidemiology of lung cancer.

Publications & conference data

No peer-reviewed publications indexed yet for this trial. Completed trials usually publish results within 12-18 months.

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Other trials of Questionnaire

Trials testing the same drug.

Other recruiting trials for Lung Cancer

Currently open trials in the same condition.

Other M.D. Anderson Cancer Center trials

Trials by the same sponsor.

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Data sources for this page

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