Last reviewed · How we verify
NCT00382421
Swiss Interventional Study on Silent Ischemia (SWISSI 1)
NA trial testing bisoprolol in Myocardial Ischemia. Completed in 1 April 2006.
Quick facts
| Lead sponsor | Luzerner Kantonsspital |
|---|---|
| Phase | NA |
| Status | Completed |
| Study type | INTERVENTIONAL |
| Allocation | randomized |
| Design | parallel |
| Masking | none |
| Primary purpose | treatment |
| Start date | 1 February 1992 |
| Estimated completion | 1 April 2006 |
| Sites | 1 location across Switzerland |
Drugs / interventions tested
- bisoprolol (BISOPROLOL) — full drug profile →
- amlodipine (amlodipine) — full drug profile →
- molsidomine (MOLSIDOMINE) — full drug profile →
- acetylsalicylic acid (acetylsalicylic acid) — full drug profile →
Conditions studied
- Myocardial Ischemia — all drugs for Myocardial Ischemia →
Sponsor
Luzerner Kantonsspital — full company profile →
Who can join
40 and older, any sex, with Myocardial Ischemia. Patients with the condition only — healthy volunteers not accepted.
What's being measured
Primary outcomes are the specific endpoints the trial is designed to prove or disprove.
- Combination of cardiac death, non-fatal myocardial infarction, unstable angina pectoris, and revascularization
Sponsor's own description
There is a lack of data on the prognostic importance of silent ischemia in totally asymptomatic subjects without history of coronary artery disease (CAD), and, particularly, on a possible benefit of medical therapy in such patients. SWISSI 1 therefore recruits totally asymptomatic subjects older than 40 years of age without any history of CAD but one cardiovascular risk factor with documented silent ischemia. Participants are randomized to open antianginal drug therapy and risk factor control versus only risk factor management and followed up for ≥ 10 years.
Publications & conference data
No peer-reviewed publications indexed yet for this trial. Completed trials usually publish results within 12-18 months.
Verify or expand the search:
- PubMed search for NCT00382421
- Europe PMC full search
- ASCO Meeting Library
- ESMO Meeting Library
- bioRxiv preprints
- medRxiv preprints
- Google Scholar
Related trials
Other recruiting trials for Myocardial Ischemia
Currently open trials in the same condition.
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- NCT07241572 — Evaluation of Perioperative Myocardial Injury in Patients Undergoing Below-Knee Lower Extremity Surgery · recruiting
- NCT06681740 — Effectiveness of Inspiratory Muscle Training for People With Ischemic Heart Disease Revascularized by Percutaneous Trans · NA · recruiting
- NCT06570759 — Time for a Diagnostic Paradigm Shift From STEMI/NSTEMI to OMI/NOMI · NA · active not recruiting
Other Luzerner Kantonsspital trials
Trials by the same sponsor.
- NCT07533578 — Chrononutrition in Preterm Infants: a Randomised Controlled Trial of Time-matched Breast Milk Feeding and Its Effects on · NA · not yet recruiting
- NCT07476079 — Optimization and Validation of Electric Acoustic Stimulation (EAS) Mapping as a Function of Residual Hearing After CI-Im · NA · not yet recruiting
- NCT07256704 — Hypnosis and Attention in Patients With a Neurological Disease (Stroke, Traumatic Brain Injury and Multiple Sclerosis) · NA · recruiting
- NCT07055139 — Digital Aftercare for Wrist and Clavicle Fractures · NA · not yet recruiting
- NCT06578598 — Comparison of Gastric Insufflation With the Classic Igel Laryngeal Mask and the New Igelplus Laryngeal Mask Using Gastri · NA · not yet recruiting
Verify against primary sources
- ClinicalTrials.gov — authoritative US registry record
- WHO ICTRP — international registry index
- EU Clinical Trials Register
- Sponsor press releases (Google)
- Trial protocol + status: ClinicalTrials.gov NCT00382421 (US National Library of Medicine, public domain)
- Drug + disease cross-links: matched in real time against Drug Landscape's normalised drug + company + condition tables
- Sponsor: as reported to ClinicalTrials.gov by Luzerner Kantonsspital
- Last refreshed: 10 October 2006
Drug Landscape aggregates and links these public records for informational use only. Always verify against the primary source before clinical or regulatory decisions. Canonical URL: https://druglandscape.com/trial/NCT00382421.
Primary sources · FDA · ClinicalTrials.gov · EMA · SEC EDGAR · ChEMBL · Wikidata · full sourcing