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NCT00347763
Strategies for the Control of Blinding Trachoma: Effect of Fly Spray
Phase 4 trial testing 10% permethrin in water applied as low volume spray in Trachoma in 350 participants. Completed in 1 October 2002.
1 September 2002
Quick facts
| Lead sponsor | Johns Hopkins University |
|---|---|
| Phase | Phase 4 |
| Status | Completed |
| Study type | INTERVENTIONAL |
| Allocation | randomized |
| Design | parallel |
| Masking | single |
| Primary purpose | prevention |
| Enrollment | 350 |
| Start date | 1 June 2000 |
| Primary completion | 1 September 2002 |
| Estimated completion | 1 October 2002 |
| Sites | 1 location across United States |
Drugs / interventions tested
- 10% permethrin in water applied as low volume spray
Conditions studied
- Trachoma — all drugs for Trachoma →
Sponsor
Johns Hopkins University
Who can join
Adults 12 Months to 8, any sex, with Trachoma. Healthy volunteers can join.
What's being measured
Primary outcomes are the specific endpoints the trial is designed to prove or disprove.
-
clinical trachoma
Time frame: 1 year
clinical grading of conjunctival photographs for follicular trachoma
Sponsor's own description
The purpose of this community-based randomized trial was to determine, in trachoma hyper-endemic communities of Tanzania, the added value of intensive spraying to control flies on the fly population and on trachoma and ocular chlamydia infection at 6 months and one year after mass antibiotic treatment.
Publications & conference data
2 peer-reviewed publications reference this trial (live from Europe PMC):
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Environmental sanitary interventions for preventing active trachoma.
Rabiu M, Alhassan MB, Ejere HO, Evans JR. · · 2012 · cited 42× · PMID 22336798 · DOI 10.1002/14651858.cd004003.pub4 -
Intensive insecticide spraying for fly control after mass antibiotic treatment for trachoma in a hyperendemic setting: a randomised trial.
West SK, Emerson PM, Mkocha H, McHiwa W, et al · · 2006 · cited 39× · PMID 16905024 · DOI 10.1016/s0140-6736(06)69203-9
Verify or expand the search:
- PubMed search for NCT00347763
- Europe PMC full search
- ASCO Meeting Library
- ESMO Meeting Library
- bioRxiv preprints
- medRxiv preprints
- Google Scholar
Related trials
Other recruiting trials for Trachoma
Currently open trials in the same condition.
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- NCT03335072 — Kebele Elimination of Trachoma for Ocular Health · Phase 4 · active not recruiting
Other Johns Hopkins University trials
Trials by the same sponsor.
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Verify against primary sources
- ClinicalTrials.gov — authoritative US registry record
- WHO ICTRP — international registry index
- EU Clinical Trials Register
- Sponsor press releases (Google)
- Trial protocol + status: ClinicalTrials.gov NCT00347763 (US National Library of Medicine, public domain)
- Publications: Europe PMC API search by NCT ID, retrieved 10 June 2026
- Drug + disease cross-links: matched in real time against Drug Landscape's normalised drug + company + condition tables
- Sponsor: as reported to ClinicalTrials.gov by Johns Hopkins University
- Last refreshed: 12 April 2013
Drug Landscape aggregates and links these public records for informational use only. Always verify against the primary source before clinical or regulatory decisions. Canonical URL: https://druglandscape.com/trial/NCT00347763.
Primary sources · FDA · ClinicalTrials.gov · EMA · SEC EDGAR · ChEMBL · Wikidata · full sourcing