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NCT00304811
Vancomycin Versus Vancomycin Plus Gentamycin For Treating Bacteremic Infection Due to Methicillin-Resistant Staphylococcus Aureus (MRSA)
Phase 4 trial testing Vancomycin in Staphylococcus Aureus in 160 participants. Completed in 1 January 2007.
1 January 2007
Quick facts
| Lead sponsor | Michael E. DeBakey VA Medical Center |
|---|---|
| Phase | Phase 4 |
| Status | Completed |
| Study type | INTERVENTIONAL |
| Allocation | randomized |
| Design | parallel |
| Masking | single |
| Enrollment | 160 |
| Start date | 1 January 2006 |
| Primary completion | 1 January 2007 |
| Estimated completion | 1 January 2007 |
| Sites | 2 locations across United States |
Drugs / interventions tested
- Vancomycin (vancomycin) — full drug profile →
- Vancomycin plus Gentamicin — full drug profile →
- Vancomycin plus Rifampin — full drug profile →
- Vancomycin plus Gentamicin plus Rifampin — full drug profile →
Conditions studied
- Staphylococcus Aureus — all drugs for Staphylococcus Aureus →
Sponsor
Michael E. DeBakey VA Medical Center
Who can join
Adults 18 to 64, any sex, with Staphylococcus Aureus. Patients with the condition only — healthy volunteers not accepted.
What's being measured
Primary outcomes are the specific endpoints the trial is designed to prove or disprove.
- Time to defervescence (24 hours of temperature <100 degrees F)
- Return of WBC to normal (<10,500)
- negative blood cultures
- discharge
Sponsor's own description
The purpose of this study is to compare the outcome of treatment for bacteremic MRSA infection with vancomycin alone, vancomycin plus gentamicin, vancomycin plus rifampin, and vancomycin plus gentamicin and rifampin.
Publications & conference data
No peer-reviewed publications indexed yet for this trial. Completed trials usually publish results within 12-18 months.
Verify or expand the search:
- PubMed search for NCT00304811
- Europe PMC full search
- ASCO Meeting Library
- ESMO Meeting Library
- bioRxiv preprints
- medRxiv preprints
- Google Scholar
Related trials
Other trials of Vancomycin
Trials testing the same drug.
- NCT07435051 — Prospective, Randomized, Multicenter Clinical Trial of Bisphosphonates Combined With Vancomycin for the Treatment of Cie · Phase 3 · not yet recruiting
- NCT06567808 — Prevention of Infections in Cardiac Surgery (PICS): a Cluster-randomized Factorial Cross-over Trial · Phase 4 · not yet recruiting
- NCT06702345 — Clostridioides Difficile Controlled Human Infection Model · NA · not yet recruiting
- NCT06716749 — Effectiveness of Adding Morphine to Intraosseous Vancomycin for Pain Control in Total Knee Arthroplasty · Phase 2 · completed
- NCT06439953 — Irrisept Solution for Instrumented Spine Surgery · NA · recruiting
Other recruiting trials for Staphylococcus Aureus
Currently open trials in the same condition.
- NCT06633588 — Decolonization Efficacy of Polyhexanide vs. Mupirocin · Phase 4 · recruiting
- NCT06749457 — A Study to Evaluate AZD7760 Safety and Pharmacokinetics in Healthy Adults (Phase I) and Adults With End-stage Kidney Dis · Phase 1, PHASE2 · recruiting
- NCT06283355 — Comparing Single Versus Repeat NMT on the Diversity of the Neonatal Nasal Microbiome · Phase 1 · recruiting
- NCT06290557 — First-in-man Single-dose and Multiple Dose Study to Evaluate the Safety, Tolerability and Efficacy ofHY-133 · Phase 1 · recruiting
- NCT05695196 — Feasibility and Safety Study of Parent-to-Child Nasal Microbiota Transplant · Phase 1 · active not recruiting
Other Michael E. DeBakey VA Medical Center trials
Trials by the same sponsor.
- NCT03820973 — Brief Cognitive Behavioral Therapy for Anxiety · NA · completed
- NCT00304863 — Addition of Lactobacillus to Metronidazole in Treatment of CDAD · Phase 4 · withdrawn
Verify against primary sources
- ClinicalTrials.gov — authoritative US registry record
- WHO ICTRP — international registry index
- EU Clinical Trials Register
- Sponsor press releases (Google)
- Trial protocol + status: ClinicalTrials.gov NCT00304811 (US National Library of Medicine, public domain)
- Drug + disease cross-links: matched in real time against Drug Landscape's normalised drug + company + condition tables
- Sponsor: as reported to ClinicalTrials.gov by Michael E. DeBakey VA Medical Center
- Last refreshed: 25 September 2009
Drug Landscape aggregates and links these public records for informational use only. Always verify against the primary source before clinical or regulatory decisions. Canonical URL: https://druglandscape.com/trial/NCT00304811.
Primary sources · FDA · ClinicalTrials.gov · EMA · SEC EDGAR · ChEMBL · Wikidata · full sourcing