NCT00144248 is a Phase 4 clinical trial of nevirapine in HIV Infections, sponsored by Boehringer Ingelheim.

Who is sponsoring NCT00144248?

NCT00144248 is sponsored by Boehringer Ingelheim.

What drugs are being tested in NCT00144248?

Interventions in NCT00144248: nevirapine.

What condition does NCT00144248 study?

NCT00144248 studies HIV Infections, Hepatic Insufficiency.

Is NCT00144248 still recruiting?

NCT00144248 is currently completed. Last updated 1 December 2023.

Last reviewed 2023-12-01 · How we verify

NCT00144248

Name: Drug Landscape Pharmaceutical Database
Creator: Drug Landscape
Published: 2026-01-01
License: https://creativecommons.org/licenses/by/4.0/

A Pharmacokinetic Study to Assess Nevirapine [Viramune] Levels in HIV Infected Patients With Impaired Hepatic Functions

Completed Phase 4 Last updated 1 December 2023

What this trial tests

Phase 4 trial testing nevirapine in HIV Infections in 51 participants. Completed.

Timeline

25 June 2004

Primary endpoint
1 June 2006

Quick facts

Lead sponsor	Boehringer Ingelheim
Phase	Phase 4
Status	Completed
Study type	INTERVENTIONAL
Allocation	randomized
Design	parallel
Masking	none
Primary purpose	treatment
Enrollment	51
Start date	25 June 2004
Primary completion	1 June 2006
Sites	8 locations across France, United States, Spain

Drugs / interventions tested

nevirapine (NEVIRAPINE) — full drug profile →

Conditions studied

HIV Infections — all drugs for HIV Infections →
Hepatic Insufficiency — all drugs for Hepatic Insufficiency →

Sponsor

Boehringer Ingelheim — full company profile →

Who can join

18 and older, any sex, with HIV Infections or Hepatic Insufficiency. Patients with the condition only — healthy volunteers not accepted.

Sponsor's own description

The objective of this study was to evaluate the steady-state clearance of nevirapine among HIV-1 positive patients with hepatic fibrosis, and to examine whether the degree of hepatic impairment influences clearance.

Publications & conference data

1 peer-reviewed publication reference this trial (live from Europe PMC):

Pharmacokinetic assessment of nevirapine and metabolites in human immunodeficiency virus type 1-infected patients with hepatic fibrosis.
Cammett AM, MacGregor TR, Wruck JM, Felizarta F, et al · · 2009 · cited 8× · PMID 19620337 · DOI 10.1128/aac.00460-09

Verify or expand the search:

Other trials of nevirapine

Trials testing the same drug.

NCT00144261 — An Open-label, Non-randomized, Single-arm Study to Investigate the Mechanism(s) by Which Nevirapine Increases Plasma HDL · Phase 4 · completed
NCT00042289 — Pharmacokinetic Study of Antiretroviral Drugs and Related Drugs During and After Pregnancy · completed

Other recruiting trials for HIV Infections

Currently open trials in the same condition.

NCT07225530 — Implementation of Screen, Treat, and Triage for Women Living With HIV in La Romana (iSTAR) · NA · recruiting
NCT07202546 — A Phase 2b Study Evaluating Oral VH4524184 Regimens in Treatment Naïve Persons With HIV-1 (INNOVATE Study) · Phase 2 · recruiting
NCT06694753 — Safety and Immunogenicity Study of Three mRNAs Encoding HIV Immunogens in Adult Participants Without HIV and in Overall · Phase 1 · recruiting
NCT07235852 — Pilot Testing Into the Feasibility of the Developed Cognitive Behavioral Therapy Intervention · NA · recruiting
NCT06665646 — Clinical Trial to Evaluate the Safety and Immunogenicity of Hiltonol, Poly-ICLC-adjuvanted CD40.HIVRI.Env (VRIPRO) in Ad · Phase 1 · recruiting

Other Boehringer Ingelheim trials

Trials by the same sponsor.

NCT07044700 — Real-world Comparative Effectiveness and Safety of Jardiance in Chinese Patients With Heart Failure of Reduced Ejection · not yet recruiting
NCT07047508 — Real-world Study to Describe the Effectiveness and Safety Outcomes of Jardiance in Chinese Patients With Heart Failure a · not yet recruiting
NCT07366034 — A Study to Find Out How Nerandomilast is Tolerated, Handled by the Body, and if it Helps Children and Adolescents With I · Phase 3 · not yet recruiting
NCT07531628 — A Study to Test How Verducatib is Taken up in the Body of Healthy Chinese Participants · Phase 1 · not yet recruiting
NCT07497087 — A Study to Test Whether Nerandomilast Helps People With Systemic Sclerosis · Phase 3 · not yet recruiting

Verify against primary sources

ClinicalTrials.gov — authoritative US registry record
WHO ICTRP — international registry index
EU Clinical Trials Register
Sponsor press releases (Google)

Data sources for this page

Trial protocol + status: ClinicalTrials.gov NCT00144248 (US National Library of Medicine, public domain)
Publications: Europe PMC API search by NCT ID, retrieved 10 June 2026
Drug + disease cross-links: matched in real time against Drug Landscape's normalised drug + company + condition tables
Sponsor: as reported to ClinicalTrials.gov by Boehringer Ingelheim
Last refreshed: 1 December 2023

Drug Landscape aggregates and links these public records for informational use only. Always verify against the primary source before clinical or regulatory decisions. Canonical URL: https://druglandscape.com/trial/NCT00144248.

Primary sources · FDA · ClinicalTrials.gov · EMA · SEC EDGAR · ChEMBL · Wikidata · full sourcing