Last reviewed · How we verify
NCT00062517
Generalized Anxiety Disorder and Social Anxiety Disorder: Their Impact on the Processing of Information and Learning
trial in Anxiety Disorders in 497 participants. Completed in 21 September 2016.
Quick facts
| Lead sponsor | National Institute of Mental Health (NIMH) |
|---|---|
| Status | Completed |
| Study type | OBSERVATIONAL |
| Enrollment | 497 |
| Start date | 5 June 2003 |
| Estimated completion | 21 September 2016 |
| Sites | 1 location across United States |
Conditions studied
- Anxiety Disorders — all drugs for Anxiety Disorders →
Sponsor
National Institute of Mental Health (NIMH)
Who can join
Adults 18 to 50, any sex, with Anxiety Disorders. Patients with the condition only — healthy volunteers not accepted.
Sponsor's own description
The purpose of this study is to increase researchers understanding of the biological basis of generalized anxiety disorder and social anxiety disorder. They will investigate how the brain activity associated with specific thoughts and feelings may play a role in these anxiety disorders. This knowledge will be used to design interventions to help those with these illnesses. To qualify for this study, participants must be evaluated via an initial telephone screening interview and material sent through the mail. Participants will then be required to make three visits to NIH. During the first visit, they will be asked questions about their general mood, degree of nervousness, thinking skills, and behavior. They will undergo a thorough physical exam, including an EKG, blood work, urinalysis, and a pregnancy test for women of childbearing potential. During the second visit, participants will spend about 2.5 hours doing various tasks while sitting and looking at a computer screen. These tasks will guide them to experience specific kinds of thoughts and emotions. Researchers will attach electrodes to the participants hands to monitor the amount of electricity conducted by the skin. The third visit will be similar to the second visit, but participants will perform the tasks while lying in a MRI scanner. Participants will be compensated up to $400 for their involvement in this study.
Publications & conference data
1 peer-reviewed publication reference this trial (live from Europe PMC):
-
Prediction Error Representation in Individuals With Generalized Anxiety Disorder During Passive Avoidance.
White SF, Geraci M, Lewis E, Leshin J, et al · · 2017 · cited 57× · PMID 27631963 · DOI 10.1176/appi.ajp.2016.15111410
Verify or expand the search:
- PubMed search for NCT00062517
- Europe PMC full search
- ASCO Meeting Library
- ESMO Meeting Library
- bioRxiv preprints
- medRxiv preprints
- Google Scholar
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Verify against primary sources
- ClinicalTrials.gov — authoritative US registry record
- WHO ICTRP — international registry index
- EU Clinical Trials Register
- Sponsor press releases (Google)
- Trial protocol + status: ClinicalTrials.gov NCT00062517 (US National Library of Medicine, public domain)
- Publications: Europe PMC API search by NCT ID, retrieved 10 June 2026
- Drug + disease cross-links: matched in real time against Drug Landscape's normalised drug + company + condition tables
- Sponsor: as reported to ClinicalTrials.gov by National Institute of Mental Health (NIMH)
- Last refreshed: 6 October 2017
Drug Landscape aggregates and links these public records for informational use only. Always verify against the primary source before clinical or regulatory decisions. Canonical URL: https://druglandscape.com/trial/NCT00062517.
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