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NCT00033969
Study of Proteins Associated With Complex Regional Pain Syndrome
trial in Complex Regional Pain Syndromes in 120 participants. Terminated before completion.
Quick facts
| Lead sponsor | National Institute of Nursing Research (NINR) |
|---|---|
| Status | Terminated |
| Study type | OBSERVATIONAL |
| Enrollment | 120 |
| Start date | 15 April 2002 |
| Estimated completion | 23 October 2014 |
| Sites | 1 location across United States |
Conditions studied
- Complex Regional Pain Syndromes — all drugs for Complex Regional Pain Syndromes →
- Healthy — all drugs for Healthy →
Sponsor
National Institute of Nursing Research (NINR)
Who can join
18 and older, any sex, with Complex Regional Pain Syndromes or Healthy. Patients with the condition only — healthy volunteers not accepted.
Sponsor's own description
This study will try to learn more about complex regional pain syndrome, or CRPS (previously known as reflex sympathetic dystrophy, spreading neuralgia, and sympathalgia), by examining the release of small proteins in the blood of patients with this condition. Patients with CRPS usually have three types of symptoms: * Sensory abnormalities increased sensitivity to pain or a painful reaction to a harmless stimulus * Perfusion abnormalities alterations in blood flow, temperature abnormality, swelling, decrease or increased nail growth, and hair and skin changes * Motor abnormalities weakness, guarding (Holding the limb in such a fashion that it minimizes accidental or intentional contact from possible sources of pain), and atrophy (wasting) The cause of CRPS is unknown, and there are no definitive diagnostic tests for the condition. Because early treatment improves the prognosis of CRPS, a test that enables early diagnosis would be important for optimal medical management. The findings of this study may contribute to the development of such a test and possibly new drug treatments. Normal healthy volunteers and patients of any age with complex regional pain syndrome who are in otherwise good general health may be eligible for this study. Participants will have a medical history, physical examination and collection of a blood sample. They will fill out several questionnaires, providing information on their health, personality, mood, pain levels, and symptoms. Participation in the study requires one outpatient clinic visit.
Publications & conference data
No peer-reviewed publications indexed yet for this trial.
Verify or expand the search:
- PubMed search for NCT00033969
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Related trials
Other recruiting trials for Complex Regional Pain Syndromes
Currently open trials in the same condition.
- NCT05986461 — Spatially Transcriptomics Reveals Molecular Signatures in CRPS · recruiting
- NCT05814497 — Supraspinal Processing of Sensory Aspects of Pain · NA · recruiting
- NCT05593237 — Transcranial Magnetic Stimulation for Chronic Neuropathic Pain · NA · active not recruiting
- NCT05337501 — Prognostic Factors for Complex Regional Pain Syndrome · NA · active not recruiting
- NCT04144972 — Closed-Loop Deep Brain Stimulation for Refractory Chronic Pain · NA · recruiting
Other National Institute of Nursing Research (NINR) trials
Trials by the same sponsor.
- NCT04141696 — A Proof-of-Concept Trial on the Effect of Ketamine on Fatigue · Phase 1, PHASE2 · completed
- NCT04883359 — Immersive VR Environments to Induce and Evaluate Cognitive Fatigability · terminated
- NCT03998358 — Characterization of Fatigue in Military Personnel With Traumatic Brain Injuries · withdrawn
- NCT03394040 — Point-of-Use Pathogen Identification Tool for Diarrhea · terminated
- NCT02931474 — Impact of GHRH on Sleep Promotion and Endocrine Regulation in Service Members Who Sustained a Traumatic Brain Injury and · Phase 2 · withdrawn
Verify against primary sources
- ClinicalTrials.gov — authoritative US registry record
- WHO ICTRP — international registry index
- EU Clinical Trials Register
- Sponsor press releases (Google)
- Trial protocol + status: ClinicalTrials.gov NCT00033969 (US National Library of Medicine, public domain)
- Drug + disease cross-links: matched in real time against Drug Landscape's normalised drug + company + condition tables
- Sponsor: as reported to ClinicalTrials.gov by National Institute of Nursing Research (NINR)
- Last refreshed: 12 December 2019
Drug Landscape aggregates and links these public records for informational use only. Always verify against the primary source before clinical or regulatory decisions. Canonical URL: https://druglandscape.com/trial/NCT00033969.
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