Patent Cliff Revenue Impact Calculator

Estimate the revenue loss a branded drug faces when patents expire. Standard pharma assumption: 80-90% revenue erosion in year 1 after generic entry; 95% by year 3. Customise for biologics (slower erosion ~30-50%).

Customise the assumptions for your specific drug. Defaults match Big Pharma analyst consensus.

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85%
93%
96%
YearRevenueLostCumulative loss

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FAQ

What is a patent cliff?
The sharp revenue decline a branded drug experiences when its primary patents expire and generic equivalents enter the market.
How fast does generic erosion happen?
For small molecules: typically 80-90% of branded sales lost in year 1, 95% by year 3. Biologics erode more slowly — 30-50% in year 1, 60-70% over 3 years.

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