What drugs target TRPM8?

3+ drugs target TRPM8, including .

What drug classes act on TRPM8?

Drug classes acting on TRPM8 include TRPM8 receptor antagonist, TRPM8 antagonist, TRPM8 channel antagonist.

3 drugs 3 in Phase 3

All drugs that target TRPM8 — marketed and clinical-stage. Includes 3 drug classes acting on this target.

CL-108 · Charleston Laboratories, Inc · TRPM8 receptor antagonist · Pain management
CL-108 is a novel, orally administered, non-opioid, non-sedating, and non-addictive analgesic.
F# PF-004390 Eye Drops · Johnson & Johnson Consumer Inc. (J&JCI) · TRPM8 antagonist · Ophthalmology
PF-004390 is a selective TRPM8 antagonist that blocks cold-sensing ion channels in the eye to reduce ocular pain and discomfort.
SHR8058 eye drops · Jiangsu HengRui Medicine Co., Ltd. · TRPM8 channel antagonist · Ophthalmology
SHR8058 is a selective TRPM8 channel antagonist that reduces ocular surface pain and irritation by blocking cold-sensitive ion channels in the eye.