TNF — Drug Target

All drugs that target TNF — marketed and clinical-stage. Includes 1 drug classes acting on this target.

Drug classes

TNF inhibitor

Phase 3 pipeline (2)

• TNFR:Fc · National Eye Institute (NEI) · TNF inhibitor · Immunology
  TNFR:Fc is a fusion protein that binds to tumor necrosis factor (TNF) and prevents it from interacting with its receptors on cell surfaces.
• administration of Cimzia® · University Hospital, Ghent · TNF inhibitor · Immunology
  Cimzia is a fully human monoclonal antibody that selectively binds to tumor necrosis factor (TNF) and blocks its interaction with cell surface TNF receptors.

Phase 2 pipeline (1)

• Baminercept alfa 4 · Biogen · TNF inhibitor · Rheumatology
  Baminercept alfa 4 is a fusion protein that targets and binds to the soluble form of tumor necrosis factor (TNF) to prevent its interaction with cell surface TNF receptors.