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administration of Cimzia®
administration of Cimzia® is a TNF inhibitor Small molecule drug developed by University Hospital, Ghent. It is currently in Phase 3 development for Moderate to severe Crohn's disease, Moderate to severe ulcerative colitis, Rheumatoid arthritis.
Cimzia is a fully human monoclonal antibody that selectively binds to tumor necrosis factor (TNF) and blocks its interaction with cell surface TNF receptors.
Cimzia is a fully human monoclonal antibody that selectively binds to tumor necrosis factor (TNF) and blocks its interaction with cell surface TNF receptors. Used for Moderate to severe Crohn's disease, Moderate to severe ulcerative colitis, Rheumatoid arthritis.
At a glance
| Generic name | administration of Cimzia® |
|---|---|
| Sponsor | University Hospital, Ghent |
| Drug class | TNF inhibitor |
| Target | TNF |
| Modality | Small molecule |
| Therapeutic area | Immunology |
| Phase | Phase 3 |
Mechanism of action
This action prevents the inflammatory effects of TNF, which is involved in the inflammatory process of various autoimmune diseases. By inhibiting TNF, Cimzia reduces inflammation and slows disease progression.
Approved indications
- Moderate to severe Crohn's disease
- Moderate to severe ulcerative colitis
- Rheumatoid arthritis
- Psoriatic arthritis
- Plaque psoriasis
Common side effects
- Upper respiratory tract infection
- Nasopharyngitis
- Headache
- Fatigue
- Injection site reaction
Key clinical trials
- SKIN Disease Profiling by an Exploratory, pRospective, Biomarker Study in dermatoloGY Practice (SKINERGY)
- IL-7 and IL-7R Expression in RA Patients With Active vs. Inactive Disease Treated With DMARD or CIMZIA (PHASE4)
- SECURE, the Cimzia ® Crohn's Disease Post-Marketing Registry
- Rheumatoid Arthritis Treatment After First Anti-TNF INvestiGation (PHASE4)
- Noninterventional Examination of Subcutaneous (sc) Tumor Necrosis Factor (TNF) Inhibitors
- National Data Bank for Rheumatic Disease Registry Study of Safety in Patients With Rheumatoid Arthritis Treated With Cimzia® or Disease-modifying Antirheumatic Drugs (DMARDs)
- Prediction of Response to Certolizumab Pegol Treatment by Functional MRI of the Brain (PHASE3)
- RABIOPRED - a Validation Study of Theranostic Test to PREDict Treatment Response of Anti-TNFα BIologicals in Rheumatoid Arthritis
Primary sources
Every claim on this page is sourced from regulatory or scientific primary sources. See our editorial policy for full methodology.
| Source | Used for |
|---|---|
| ClinicalTrials.gov | Trial enrolment, design, endpoints, results |
Competitive intelligence
For the full competitive landscape — auto-detected comparators, recent regulatory actions across the set, upcoming PDUFA, patent timeline, sponsor landscape:
- administration of Cimzia® CI brief — competitive landscape report
- administration of Cimzia® updates RSS · CI watch RSS
- University Hospital, Ghent portfolio CI
Frequently asked questions about administration of Cimzia®
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Related
- Drug class: All TNF inhibitor drugs
- Target: All drugs targeting TNF
- Manufacturer: University Hospital, Ghent — full pipeline
- Therapeutic area: All drugs in Immunology
- Indication: Drugs for Moderate to severe Crohn's disease
- Indication: Drugs for Moderate to severe ulcerative colitis
- Indication: Drugs for Rheumatoid arthritis
- Compare: administration of Cimzia® vs similar drugs
- Pricing: administration of Cimzia® cost, discount & access