Substance-P receptor — Drug Target

All drugs that target Substance-P receptor — marketed and clinical-stage. Includes 3 drug classes acting on this target.

Drug classes

Serotonin-3 Receptor Antagonist [EPC] · Substance P/Neurokinin-1 Receptor Antagonist [EPC] · Substance P/Neurokinin-1 Receptor Antagonist

Marketed (5)

• Akynzeo · Helsinn Hlthcare · Serotonin-3 Receptor Antagonist [EPC] · Oncology
  Akynzeo works by blocking the substance P/neurokinin-1 receptor to prevent nausea and vomiting caused by chemotherapy.
• Emend · Merck & Co. · Substance P/Neurokinin-1 Receptor Antagonist [EPC] · Oncology
  Emend works by blocking the action of a natural substance called substance P, which is involved in the vomiting reflex.
• Akynzeo · Helsinn Hlthcare · Serotonin-3 Receptor Antagonist [EPC] · Oncology
  Akynzeo works by blocking the action of substance-P, a natural substance in the body that triggers nausea and vomiting.
• Emend · Substance P/Neurokinin-1 Receptor Antagonist · Oncology
  Emend blocks the action of substance P, a natural substance that can trigger nausea and vomiting.
• Varubi · Tersera · Substance P/Neurokinin-1 Receptor Antagonist · Oncology
  Varubi works by blocking the substance-P receptor, a key player in the body's response to chemotherapy-induced nausea and vomiting.