Sodium-chloride cotransporter and Mineralocorticoid receptor — Drug Target

All drugs that target Sodium-chloride cotransporter and Mineralocorticoid receptor — marketed and clinical-stage. Includes 1 drug classes acting on this target.

Drug classes

Loop diuretic and potassium-sparing diuretic

Phase 3 pipeline (1)

• Torsemide Tablets and Spironolactone Tablets · Sarfez Pharmaceuticals, Inc. · Loop diuretic and potassium-sparing diuretic · Cardiovascular
  Torsemide is a thiazide-like diuretic that works by inhibiting the sodium-chloride cotransporter in the distal convoluted tubule of the kidneys, leading to increased urine production and reduced fluid volume. Spironolactone is a potassium-sparing diuretic that works by antagonizing the mineralocorticoid receptor, leading to increased sodium excretion and reduced potassium loss.