Loop diuretic and potassium-sparing diuretic

This page covers all Loop diuretic and potassium-sparing diuretic drugs tracked by Drug Landscape: marketed products and active clinical-stage compounds, targeting Sodium-chloride cotransporter and Mineralocorticoid receptor, Sodium-potassium-chloride cotransporter (NKCC2) and Aldosterone receptor.

Targets

Sodium-chloride cotransporter and Mineralocorticoid receptor · Sodium-potassium-chloride cotransporter (NKCC2) and Aldosterone receptor

Phase 3 pipeline (2)

• Torsemide Tablets and Spironolactone Tablets · Sarfez Pharmaceuticals, Inc. · Cardiovascular
  Torsemide is a thiazide-like diuretic that works by inhibiting the sodium-chloride cotransporter in the distal convoluted tubule of the kidneys, leading to increased urine production and reduced fluid volume. Spironolactone is a potassium-sparing diuretic that works by antagonizing the mineralocorticoid receptor, leading to increased sodium excretion and reduced potassium loss.
• Torsemide and Spironolactone tablet · Sarfez Pharmaceuticals, Inc. · Cardiovascular
  Torsemide is a loop diuretic that works by inhibiting the sodium-potassium-chloride cotransporter in the ascending limb of the loop of Henle, while spironolactone is a potassium-sparing diuretic that works by antagonizing the aldosterone receptor.

Patent intelligence

• loop diuretic and potassium sparing diuretic patent landscape — aggregated cliff calendar, attackable patents, originator estates