What drugs target SARS-CoV-2 spike protein and other viral antigens?

8+ drugs target SARS-CoV-2 spike protein and other viral antigens, including Inactivated SARS-CoV-2 Vaccine (Vero cell）, COVAX only (1st and 2nd dose), CCP.

What drug classes act on SARS-CoV-2 spike protein and other viral antigens?

Drug classes acting on SARS-CoV-2 spike protein and other viral antigens include inactivated viral vaccine, Inactivated viral vaccine, Convalescent plasma.

SARS-CoV-2 spike protein and other viral antigens — Drug Target

8 drugs 3 marketed 5 in Phase 3

All drugs that target SARS-CoV-2 spike protein and other viral antigens — marketed and clinical-stage. Includes 3 drug classes acting on this target.

Drug classes

inactivated viral vaccine · Inactivated viral vaccine · Convalescent plasma

Marketed (3)

Inactivated SARS-CoV-2 Vaccine (Vero cell） · Sinovac Research and Development Co., Ltd. · inactivated viral vaccine · Immunology / Infectious Disease
This inactivated vaccine stimulates the immune system to produce antibodies and cellular immunity against SARS-CoV-2 by presenting whole inactivated viral particles.
COVAX only (1st and 2nd dose) · China National Biotec Group Company Limited · Inactivated viral vaccine · Immunology / Infectious Disease
COVAX is an inactivated COVID-19 vaccine that stimulates the immune system to produce antibodies and cellular immunity against SARS-CoV-2 by presenting inactivated viral particles.
CCP · Metro Infectious Disease Consultants · Convalescent plasma · Infectious Disease
CCP is a convalescent plasma product that provides passive immunotherapy through antibodies from recovered COVID-19 patients to treat active SARS-CoV-2 infection.

Phase 3 pipeline (5)

CoronaVac/CoronaVac · Institut Pasteur de Tunis · Inactivated viral vaccine · Immunology / Infectious Disease
CoronaVac is an inactivated SARS-CoV-2 vaccine that stimulates the immune system to produce antibodies and cellular immunity against the virus.
CoronaVac Biofarma COVID-19 Vaccine · Dr. Soetomo General Hospital · Inactivated viral vaccine · Immunology / Infectious Disease
CoronaVac is an inactivated whole-virus COVID-19 vaccine that stimulates the immune system to produce antibodies and cellular immunity against SARS-CoV-2.
Inactivated SARS-CoV-2 vaccine · Jiangsu Province Centers for Disease Control and Prevention · Inactivated viral vaccine · Immunology / Infectious Disease
This inactivated vaccine trains the immune system to recognize and neutralize SARS-CoV-2 by presenting killed viral particles that cannot cause infection.
Sinopharm BIBP · Vaxxinity, Inc. · Inactivated viral vaccine · Immunology / Infectious Disease
Sinopharm BIBP is a COVID-19 inactivated vaccine that stimulates immune responses against SARS-CoV-2 by presenting inactivated viral particles to the immune system.
CoronaVac Vaccine · Clover Biopharmaceuticals AUS Pty · Inactivated viral vaccine · Immunology / Infectious Disease
CoronaVac is an inactivated SARS-CoV-2 vaccine that stimulates the immune system to produce antibodies and cellular immunity against the virus.