S1P1 — Drug Target
All drugs that target S1P1 — marketed and clinical-stage. Includes 4 drug classes acting on this target.
Drug classes
S1P receptor modulator · S1P1 receptor modulator · S1P1 receptor antagonist · Sphingosine 1-phosphate receptor modulator
Marketed (1)
- Group S+T · Huazhong University of Science and Technology · S1P receptor modulator · Immunology
This drug targets the S1P receptor to modulate lymphocyte trafficking and reduce inflammation.
Phase 3 pipeline (11)
- SAIT101 · Archigen Biotech Limited · S1P1 receptor modulator · Immunology
SAIT101 is a small molecule that targets the S1P1 receptor. - TDT067 · Celtic Pharma Development Services · S1P1 receptor modulator · Autoimmune diseases
TDT067 is a small molecule that targets the S1P1 receptor. - zilucoplan (RA101495) · UCB Biopharma SRL · S1P receptor modulator · Immunology
Zilucoplan is a sphingosine 1-phosphate receptor modulator. - KP-100IT · Kringle Pharma, Inc. · S1P1 receptor modulator · Immunology
KP-100IT is a small molecule that targets the S1P1 receptor. - RO0503821 (1x/4 Weeks) · Hoffmann-La Roche · S1P receptor modulator · Immunology
RO0503821 is a small molecule that targets the S1P1 receptor. - Elizaria® · AO GENERIUM · S1P receptor modulator · Multiple Sclerosis
Elizaria is a small molecule that targets the S1P1 receptor. - JYB1904 · Jemincare · S1P1 receptor antagonist · Autoimmune diseases
JYB1904 is a small molecule targeting the S1P1 receptor. - TVAV-008 · Grand Theravac Life Sciences (Nanjing) Co., Ltd. · S1P1 receptor modulator · Immunology
TVAV-008 is a small molecule that targets the S1P1 receptor. - RPC1063 · Celgene · S1P receptor modulator · Oncology
RPC1063 is a sphingosine 1-phosphate receptor modulator. - JMKX001899 · Jemincare · S1P1 receptor modulator · Immunology
JMKX001899 is a small molecule that targets the S1P1 receptor. - NU100 · Nuron Biotech Inc. · S1P1 receptor modulator · Multiple Sclerosis
NU100 is a small molecule that targets the S1P1 receptor.
Phase 2 pipeline (14)
- Apilimod Dimesylate Capsule · OrphAI Therapeutics · Sphingosine 1-phosphate receptor modulator · Immunology
Apilimod Dimesylate Capsule is a sphingosine 1-phosphate receptor modulator. - AZD2811 · AstraZeneca · S1P1 receptor modulator · Oncology
AZD2811 is a small molecule that targets the S1P1 receptor. - BMB-101 · Bright Minds Biosciences Pty Ltd · S1P1 receptor modulator · Immunology
BMB-101 is a small molecule that targets the S1P1 receptor. - GSK1521498 · GlaxoSmithKline · S1P receptor modulator · Autoimmune diseases
GSK1521498 is a small molecule drug that targets the S1P1 receptor. - DWN12088 · Daewoong Pharmaceutical Co. LTD. · S1P1 receptor modulator · Immunology
DWN12088 is a small molecule that targets the S1P1 receptor. - ATS907 · Altheos, Inc. · S1P1 receptor antagonist · Autoimmune diseases
ATS907 is a small molecule that targets the S1P1 receptor. - GSK2197870A · GlaxoSmithKline · S1P1 receptor modulator · Autoimmune diseases
GSK2197870A is a small molecule that targets the S1P1 receptor. - ACT01 · Promius Pharma, LLC · S1P receptor modulator · Multiple Sclerosis
ACT01 is a small molecule that targets the S1P receptor. - AD 337 · Sosei · S1P receptor modulator · Autoimmune diseases
AD 337 is a small molecule targeting the S1P1 receptor. - FNP-223 · Ferrer Internacional S.A. · S1P1 receptor modulator · Immunology
FNP-223 is a small molecule that targets the S1P1 receptor. - BOL-303242-X · Bausch & Lomb Incorporated · S1P receptor modulator · Ophthalmology
BOL-303242-X is a small molecule that targets the S1P1 receptor. - AGN-151607 · AbbVie · S1P1 receptor modulator · Autoimmune diseases
AGN-151607 is a small molecule that targets the S1P1 receptor. - BL-7040 · BioLineRx, Ltd. · S1P1 receptor modulator · Autoimmune diseases
BL-7040 is a small molecule that acts as a sphingosine-1-phosphate receptor 1 (S1P1) modulator. - ABBV-CLS-628 · AbbVie · S1P1 receptor antagonist · Autoimmune diseases
ABBV-CLS-628 is a small molecule targeting the S1P1 receptor.