Plasmodium falciparum heme metabolism and protein synthesis — Drug Target

All drugs that target Plasmodium falciparum heme metabolism and protein synthesis — marketed and clinical-stage. Includes 1 drug classes acting on this target.

Drug classes

Antimalarial combination therapy

Marketed (1)

• Coadministered Artesunate plus Amodiaquine · Professor Anders Björkman · Antimalarial combination therapy · Infectious Disease
  Artesunate and amodiaquine work synergistically to kill malaria parasites through distinct mechanisms: artesunate generates reactive oxygen species that damage parasite proteins and DNA, while amodiaquine inhibits parasite heme detoxification.