What drugs target P-selectin?

3+ drugs target P-selectin, including Crizanlizumab Injection, Selg1, ADAKVEO.

What drug classes act on P-selectin?

Drug classes acting on P-selectin include P-selectin inhibitor monoclonal antibody, Selectin Blocker [EPC].

3 drugs 3 marketed

All drugs that target P-selectin — marketed and clinical-stage. Includes 2 drug classes acting on this target.

Crizanlizumab Injection · Matthew Neal MD · P-selectin inhibitor monoclonal antibody · Hematology/Oncology
Crizanlizumab is a monoclonal antibody that binds to P-selectin on the surface of platelets and endothelial cells, blocking platelet-endothelial interactions and reducing vaso-occlusive crises in sickle cell disease.
Selg1 · Novartis · Selectin Blocker [EPC] · Metabolic
Selg1 works by binding to P-selectin, preventing it from interacting with its ligands.
ADAKVEO · NOVARTIS PHARMS CORP · Selectin Blocker [EPC] · Other