Orexin receptor — Drug Target

All drugs that target Orexin receptor — marketed and clinical-stage. Includes 2 drug classes acting on this target.

Drug classes

Orexin receptor antagonist · orexin receptor antagonist

Phase 2 pipeline (7)

• ACT-541468 · Idorsia Pharmaceuticals Ltd. · Orexin receptor antagonist · Sleep disorders
  ACT-541468 is a selective orexin receptor antagonist.
• AD504 · Apnimed · Orexin receptor antagonist · Neurology
  AD504 is an oral small molecule that targets the orexin receptor to treat narcolepsy.
• AD036 · Apnimed · orexin receptor antagonist · Neurology
  AD036 is a small molecule that targets the orexin receptor to treat narcolepsy.
• AD109 dose1- A · Apnimed · orexin receptor antagonist · Neurology
  AD109 is a small molecule that targets the orexin receptor to treat narcolepsy.
• Lemborexant tablets · Shanghai Mental Health Center · Orexin receptor antagonist · Neurology
  Treats insomnia by modulating orexin receptors
• AD109 dose2- B · Apnimed · orexin receptor antagonist · Neurology
  AD109 is a small molecule targeting the orexin receptor for the treatment of narcolepsy.
• AD182 · Apnimed · orexin receptor antagonist · Neurology
  AD182 is a small molecule targeting the orexin receptor for the treatment of narcolepsy.