What drugs target MT1 and MT2 melatonin receptors?

12+ drugs target MT1 and MT2 melatonin receptors, including Ramelteon (RozeremR), Melatonin(Circadin®), Melatonin PR, transdermal therapeutic system- melatonin., melatonin in children premedication.

What drug classes act on MT1 and MT2 melatonin receptors?

Drug classes acting on MT1 and MT2 melatonin receptors include Melatonin receptor agonist.

MT1 and MT2 melatonin receptors — Drug Target

12 drugs 10 marketed 2 in Phase 3

All drugs that target MT1 and MT2 melatonin receptors — marketed and clinical-stage. Includes 1 drug classes acting on this target.

Drug classes

Melatonin receptor agonist

Marketed (10)

Ramelteon (RozeremR) · University of Sao Paulo · Melatonin receptor agonist · Neurology / Sleep Medicine
Ramelteon is a melatonin receptor agonist that binds to MT1 and MT2 receptors in the brain to promote sleep onset and maintain circadian rhythm.
Melatonin(Circadin®) · KIMJisun · Melatonin receptor agonist · Neurology / Sleep Medicine
Melatonin is a natural hormone that binds to melatonin receptors (MT1 and MT2) in the brain to regulate circadian rhythm and promote sleep.
Melatonin PR · Seoul National University Hospital · Melatonin receptor agonist · Neurology / Sleep Medicine
Melatonin PR is a prolonged-release formulation of melatonin that binds to melatonin receptors to regulate circadian rhythm and promote sleep.
transdermal therapeutic system- melatonin. · Ain Shams University · Melatonin receptor agonist · Neurology / Sleep Medicine
Melatonin binds to melatonin receptors (MT1 and MT2) to regulate circadian rhythm and promote sleep.
melatonin in children premedication · Azienda Ospedaliera Universitaria Policlinico "G. Martino" · Melatonin receptor agonist · Anesthesia/Perioperative Medicine
Melatonin binds to melatonin receptors (MT1 and MT2) in the brain to promote sleep and reduce anxiety in pediatric patients before medical procedures.
Sublingual Melatonin · Al-Azhar University · Melatonin receptor agonist · Neurology / Sleep Medicine
Melatonin binds to melatonin receptors (MT1 and MT2) in the brain to regulate circadian rhythm and promote sleep.
Melatonin injection · Imperial College London · Melatonin receptor agonist · Neurology / Sleep Medicine
Melatonin binds to melatonin receptors (MT1 and MT2) to regulate circadian rhythm and promote sleep-wake cycle normalization.
Melatonin treatment · Federal State Budgetary Institution, V. A. Almazov Federal North-West Medical Research Centre, of the Ministry of Health · Melatonin receptor agonist · Neurology / Sleep Medicine
Melatonin is a naturally occurring hormone that binds to melatonin receptors to regulate circadian rhythm and promote sleep.
Oral Bedtime Melatonin · Hospital San Carlos, Madrid · Melatonin receptor agonist · Neurology / Sleep Medicine
Melatonin binds to melatonin receptors (MT1 and MT2) in the suprachiasmatic nucleus to regulate circadian rhythm and promote sleep onset.
Melatonin Patches · Ain Shams University · Melatonin receptor agonist · Neurology / Sleep Medicine
Melatonin binds to melatonin receptors (MT1 and MT2) to regulate circadian rhythm and promote sleep.

Phase 3 pipeline (2)

N-acetyl-5-methoxytryptamine · University of Baghdad · Melatonin receptor agonist · Neurology; Sleep disorders
N-acetyl-5-methoxytryptamine (melatonin) acts as a melatonin receptor agonist to regulate circadian rhythms and provide antioxidant and anti-inflammatory effects.
Oral Melatonin (4 mg) · Woolcock Institute of Medical Research · Melatonin receptor agonist · Neurology / Sleep Medicine
Melatonin binds to melatonin receptors (MT1 and MT2) to regulate circadian rhythm and promote sleep.