Histone deacetylases — Drug Target

All drugs that target Histone deacetylases — marketed and clinical-stage. Includes 1 drug classes acting on this target.

Drug classes

Histone deacetylase inhibitor

Phase 3 pipeline (4)

• SHR2554 analog tablets; Chidamide · Jiangsu HengRui Medicine Co., Ltd. · Histone deacetylase inhibitor · Oncology
  Chidamide is a histone deacetylase inhibitor that works by blocking the activity of histone deacetylases, leading to the accumulation of acetylated histones and the activation of tumor suppressor genes.
• Purinostat Mesylate for Injection · Chengdu Zenitar Biomedical Technology Co., Ltd · Histone deacetylase inhibitor · Oncology
  Purinostat Mesylate for Injection is a histone deacetylase inhibitor that works by blocking the activity of histone deacetylases, leading to the accumulation of acetylated histones and changes in gene expression.
• XNW5004 placebo; Chidamide · Evopoint Biosciences Inc. · Histone deacetylase inhibitor · Oncology
  Chidamide is a histone deacetylase inhibitor that works by blocking the activity of histone deacetylases, leading to the accumulation of acetylated histones and the activation of tumor suppressor genes.
• placebo to vorinostat · Merck Sharp & Dohme LLC · Histone deacetylase inhibitor · Oncology
  Vorinostat is a histone deacetylase inhibitor that works by blocking the action of histone deacetylases, leading to the accumulation of acetylated histones and altered gene expression.