Histamine H3 receptor — Drug Target

All drugs that target Histamine H3 receptor — marketed and clinical-stage. Includes 5 drug classes acting on this target.

Drug classes

histamine · Quinolone Antimicrobial [EPC] · histamine H3 receptor inverse agonist · Histamine H3 receptor inverse agonist · betahistine

Marketed (3)

• Wakix · Harmony · Neuroscience
  Wakix works by blocking histamine H3 receptors in the brain, allowing more histamine to be available to regulate sleep-wake cycles.
• Eramin · Eli Lilly · histamine · Oncology
• Floxin · Quinolone Antimicrobial [EPC] · Metabolic

Phase 2 pipeline (3)

• ACP-211 · ACADIA Pharmaceuticals Inc. · histamine H3 receptor inverse agonist · Neurology
  ACP-211 is a selective histamine H3 receptor inverse agonist.
• ACP-104 · ACADIA Pharmaceuticals Inc. · Histamine H3 receptor inverse agonist · Neurology
  ACP-104 is a selective histamine H3 receptor inverse agonist.
• Merislon · betahistine · Other
  Merislon works by binding to the histamine H3 receptor, which helps to regulate the balance of fluids in the inner ear.