What drugs target HDACs?

1+ drugs target HDACs, including Istodax.

What drug classes act on HDACs?

Drug classes acting on HDACs include Histone Deacetylase Inhibitor.

HDACs — Drug Target

Name: Drug Landscape Pharmaceutical Database
Creator: Drug Landscape
Published: 2026-01-01
License: https://creativecommons.org/licenses/by/4.0/

1 drugs 1 marketed

All drugs that target HDACs — marketed and clinical-stage. Includes 1 drug classes acting on this target.

Drug classes

Histone Deacetylase Inhibitor

Marketed (1)

Istodax · Teva Pharms Usa Inc · Histone Deacetylase Inhibitor · Oncology
Romidepsin inhibits HDACs, leading to increased acetylation of histones and non-histone proteins, causing cell cycle arrest and apoptosis in cancer cells.