Estrogen receptor and GnRH receptor — Drug Target

All drugs that target Estrogen receptor and GnRH receptor — marketed and clinical-stage. Includes 1 drug classes acting on this target.

Drug classes

Selective estrogen receptor modulator (SERM) and Gonadotropin-releasing hormone (GnRH) analogue

Phase 3 pipeline (1)

• Tamoxifen and GnRH analogue · GBG Forschungs GmbH · Selective estrogen receptor modulator (SERM) and Gonadotropin-releasing hormone (GnRH) analogue · Oncology
  Tamoxifen acts as a selective estrogen receptor modulator (SERM) to inhibit estrogen's proliferative effects on breast cancer cells, while GnRH analogue works by downregulating GnRH receptors in the pituitary gland, leading to decreased gonadotropin secretion and subsequently reduced estrogen production.