Endothelin receptor — Drug Target

All drugs that target Endothelin receptor — marketed and clinical-stage. Includes 1 drug classes acting on this target.

Drug classes

Endothelin receptor antagonist

Phase 2 pipeline (4)

• Atrasentan low dose group · AbbVie (prior sponsor, Abbott) · Endothelin receptor antagonist · Cardiovascular
  Endothelin receptor antagonist
• Atrasentan high dose group · AbbVie (prior sponsor, Abbott) · Endothelin receptor antagonist · Cardiovascular
  Atrasentan is an endothelin receptor antagonist that blocks the action of endothelin-1, a potent vasoconstrictor.
• Bosentan group · Elpen Pharmaceutical Co. Inc. · Endothelin receptor antagonist · Cardiovascular
  Bosentan is an endothelin receptor antagonist that works by blocking the action of endothelin-1, a potent vasoconstrictor.
• Assigned pulmonary hypertension medication · Bayer · Endothelin receptor antagonist · Cardiovascular
  This drug works by inhibiting the action of endothelin-1, a potent vasoconstrictor.