Cytochrome P450 1A2 — Drug Target

All drugs that target Cytochrome P450 1A2 — marketed and clinical-stage. Includes 5 drug classes acting on this target.

Drug classes

Alkylating Drug · Antirheumatic Agent [EPC] · Photoactivated Radical Generator [EPC] · Anthelmintic · artemisinin

Marketed (4)

• Hexalen · Eisai · Alkylating Drug · Oncology
• Arava · Sanofi · Antirheumatic Agent [EPC] · Immunology
  Arava works by inhibiting the enzyme Cytochrome P450 1A2, which is involved in the production of inflammatory chemicals in the body.
• Oxsoralen-Ultra · Bausch Health · Photoactivated Radical Generator [EPC] · Oncology
  Oxsoralen-Ultra works by generating free radicals when exposed to ultraviolet A (UVA) light, which helps to slow down the growth of skin cells and reduce inflammation.
• Bovizole · Anthelmintic · Infectious Disease

Phase 3 pipeline (1)

• Artemef · artemisinin · Infectious Disease
  Artemef works by generating reactive oxygen species that rapidly kill malaria parasites.