COX-1 and COX-2 enzymes — Drug Target

All drugs that target COX-1 and COX-2 enzymes — marketed and clinical-stage. Includes 3 drug classes acting on this target.

Drug classes

Nonsteroidal anti-inflammatory drug (NSAID) combination · Nonsteroidal anti-inflammatory drug (NSAID) · Topical NSAID

Marketed (3)

• aspirin + celecoxib · Seoul National University Hospital · Nonsteroidal anti-inflammatory drug (NSAID) combination · Rheumatology / Pain Management
  This combination inhibits cyclooxygenase (COX) enzymes to reduce prostaglandin synthesis and inflammation through dual NSAID action.
• Topical diclofenac sodium gel · Guang'anmen Hospital of China Academy of Chinese Medical Sciences · Nonsteroidal anti-inflammatory drug (NSAID) · Pain Management / Rheumatology
  Diclofenac sodium inhibits cyclooxygenase (COX) enzymes to reduce prostaglandin synthesis, thereby decreasing inflammation and pain at the site of topical application.
• Voltaren® Gel · Glenmark Pharmaceuticals Ltd. India · Topical NSAID · Pain Management / Rheumatology
  Voltaren Gel is a topical nonsteroidal anti-inflammatory drug (NSAID) that inhibits cyclooxygenase (COX) enzymes to reduce local inflammation and pain at the site of application.