Complement C5 — Drug Target
All drugs that target Complement C5 — marketed and clinical-stage. Includes 3 drug classes acting on this target.
Drug classes
Complement Inhibitor [EPC] · Complement Inhibitors · Complement C5 inhibitor
Marketed (8)
- Ultomiris · AstraZeneca · Complement Inhibitor [EPC] · Cardiovascular
Ultomiris blocks the action of Complement C5 to prevent inflammation and damage to red blood cells. - Izervay · Astellas Pharma · Immunology
Izervay works by binding to and inhibiting the activity of Complement C5, a protein involved in the immune response. - Avacincaptad · Aviceda Therapeutics, Inc. · Ophthalmology
- Veopoz · Regeneron · Complement Inhibitor [EPC] · Immunology
Veopoz works by blocking the activity of Complement C5, a protein that contributes to inflammation. - AVACINCAPTAD PEGOL SODIUM · Complement Inhibitors · Immunology
- ULTOMIRIS · ALEXION PHARM · Other
- Ultomiris · Alexion Pharmaceuticals, Inc. · Other
- Soliris · Apellis Pharmaceuticals, Inc. · Neuroscience
Phase 3 pipeline (1)
- BOL-303259-X · Bausch & Lomb Incorporated · Complement C5 inhibitor · Ophthalmology
BOL-303259-X is a small molecule that inhibits the complement C5 pathway to reduce inflammation and tissue damage in the eye.