5-alpha-reductase — Drug Target

All drugs that target 5-alpha-reductase — marketed and clinical-stage. Includes 3 drug classes acting on this target.

Drug classes

Phytotherapeutic · 5-alpha reductase inhibitor · 5-alpha-reductase inhibitor

Phase 3 pipeline (2)

• Saw Palmetto - first 24 weeks · University of Alabama at Birmingham · Phytotherapeutic · Urology
  Saw palmetto may inhibit the conversion of testosterone to dihydrotestosterone (DHT), a hormone involved in hair loss and prostate issues.
• Saw Palmetto - weeks 24 - 48 · University of Alabama at Birmingham · Phytotherapeutic · Urology
  Saw palmetto may inhibit the conversion of testosterone to dihydrotestosterone (DHT), a hormone linked to benign prostatic hyperplasia (BPH).

Phase 2 pipeline (2)

• CB-03-01 · Intrepid Therapeutics, Inc. · 5-alpha reductase inhibitor · Dermatology
  CB-03-01 is a selective androgen receptor modulator (SARM) that inhibits 5-alpha reductase to reduce DHT-driven androgenetic alopecia.
• 5ARI · GlaxoSmithKline · 5-alpha-reductase inhibitor · Urology
  5-alpha-reductase inhibitor