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Saw Palmetto - first 24 weeks

University of Alabama at Birmingham · Phase 3 active Small molecule

Saw palmetto may inhibit the conversion of testosterone to dihydrotestosterone (DHT), a hormone involved in hair loss and prostate issues.

Saw palmetto may inhibit the conversion of testosterone to dihydrotestosterone (DHT), a hormone involved in hair loss and prostate issues. Used for Benign prostatic hyperplasia (BPH), Androgenetic alopecia.

At a glance

Generic nameSaw Palmetto - first 24 weeks
SponsorUniversity of Alabama at Birmingham
Drug classPhytotherapeutic
Target5-alpha-reductase
ModalitySmall molecule
Therapeutic areaUrology
PhasePhase 3

Mechanism of action

The exact mechanism of saw palmetto's effects on hair loss and prostate issues is not fully understood, but it is thought to involve the inhibition of 5-alpha-reductase, an enzyme that converts testosterone to DHT. This may lead to a decrease in DHT levels, which in turn may slow or stop hair loss and alleviate prostate issues.

Approved indications

Common side effects

Key clinical trials

Primary sources

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SourceUsed for
ClinicalTrials.govTrial enrolment, design, endpoints, results

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