GB2183661A — Method for obtaining dna, rna, peptides, polypeptides or proteins by means of a dna recombinant technique

USPTO Abstract

Genes at least partially composed of stochastic synthetic polynucleotides are simultaneously produced wihtin the same medium, the genes thus obtained are introduced into host cells; the independent strains of modified host cells enclosing said genes are simultaneously grown, so as to clone the stochastic genes and to promote the production of the proteins expressed by each of said stochastic genes; the strains of modified host cells are screened and/or selected so as to identify the strains producing peptides or polypeptides showing at least a given property; the identified strains are isolated and grown so as to produce at least a peptide or polypeptide showing said property. Analogously, stochastic DNA orRNA sequences showing at least a desired property can be produced by screening and selecting strains of modified host cells so as to identify the strains enclosing in their genome said DNA or RNA sequences.