EP Patent

EP1988397A1 — Compositions and method for stabilizing transthyretin and inhibiting transthyretin misfolding

Assigned to Scripps Research Institute · Expires 2008-11-05 · 18y expired

What this patent protects

Kinetic stabilization of the native state of transthyretin is an effective mechanism for preventing protein misfolding. Because transthyretin misfolding plays an important role in transthyretin amyloid diseases, inhibiting such misfolding can be used as an effective treatment or …

USPTO Abstract

Kinetic stabilization of the native state of transthyretin is an effective mechanism for preventing protein misfolding. Because transthyretin misfolding plays an important role in transthyretin amyloid diseases, inhibiting such misfolding can be used as an effective treatment or prophylaxis for such diseases. Treatment methods, screening methods, as well as specific transthyretin stabilizing compounds are disclosed.

Drugs covered by this patent

Patent Metadata

Patent number
EP1988397A1
Jurisdiction
EP
Classification
—
Expires
2008-11-05
Drug substance claim
No
Drug product claim
No
Assignee
Scripps Research Institute
Source
FDA Orange Book + USPTO grounding via Google Patents

Bibliographic data sourced from FDA Orange Book + USPTO public records. Plain-English summary generated by AI grounded in source text. Patent term extensions (PTR, SPC, pediatric) may shift the effective expiry. Not legal advice.

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